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EC number: 254-179-7
CAS number: 38888-98-1
Measured values for the bioconcentration factor are available for SAS-296. 1,4-Dimethyl-2-(1-phenylethyl)benzene (SAS-296) was tested in a flow-through system in accordance with OECD Test Guideline 305 for 42 days with two concentration levels (1 ppb and 0.1 ppb). A stock solution used in the test was prepared without dispersant but direct dissolution in the test water. BCF values at steady state were determined as 540 for the higher and 620 for the lower concentration level.The bioconcentration factor (BCF) of members of the diphenylmethan category was also calculated by the EPI (Estimation Programs Interface) Suite™, a Windows®-based suite of physical/chemical property and environmental fate estimation programs developed by the EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC).Following results for the bioconcentration factor BCF (L/kg wet weight; upper, mid and lower trophic level) were obtained:1,1-DPE: 325 - 420Benzyltoluene: 725 - 1048Phenyl-tolyl-ethane: 1253- 1732SAS-296: 855 - 1345SAS-305: 2322 - 2596
tested in a flow-through system in accordance with OECD Test Guideline
305 for 42 days with two concentration levels (1 ppb and 0.1 ppb). A
stock solution used in the test was prepared without dispersant but
direct dissolution in the test water. BCF values at steady state were
determined as 540 for the higher and 620 for the lower concentration
addition, data is available from a reliable QSAR model.
of 1,1’-DPE is not expected since the criterion for considering
substances as being not bioaccumulative (i.e. unlikely to have a
BCF > 2,000) are met as can be derived from BCF calculation: The BCF of
325 to 420 for 1,1’-DPE fits well
within the lower range of calculated values for BCF. As can be expected
a clear correlation exists between molecular weight and the BCF. No
further testing is required.
For detailed read across rationale and
justification see section 13, Read across document.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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