Registration Dossier
Registration Dossier
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EC number: 233-713-2 | CAS number: 10326-41-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Water solubility:
- 86.1 other: % w/w
- Temp.:
- 20 °C
- pH:
- >= 0 - <= 14
- Remarks on result:
- other: Lactic acid is soluble in water in all ratios. Solubility is not dependent on pH. pH of the solution will depend on the concentration, but at higher concentrations an ever larger fraction of the lactic acid will form oligomers.
- Water solubility:
- 93 other: % w/w
- Temp.:
- 35 °C
- pH:
- >= 0 - <= 14
- Remarks on result:
- other: Lactic acid is soluble in water in all ratios. Solubility is not dependent on pH. pH of the solution will depend on the concentration, but at higher concentrations an ever larger fraction of the lactic acid will form oligomers.
- Details on results:
- Stable: yes
pKa: 3.85 at 25 °C
Temperature effects: Solubility 76.0 % at 0 °C; 81.3 % at 10 °C; 95.1 % at 40 °C
Degradation products: no - Conclusions:
- Aqueous solubility of lactic acid is 86 % w/w at 20 °C. At 35 °C, solubility is 93 %. Apparently the viscosity of the solution is such that upon cooling, no lactic acid crystallizes from a 93 % solution, but all lactic acid remains in a supercooled solution state.
- Executive summary:
L-(+)-lactic acid is miscible with water up to a content of 86 – 93 %, dependent on temperature.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reference
Description of key information
Lactic acid is extremely well soluble in water, up to 86 %, i.e. approximately 860 g/L.
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Key value for chemical safety assessment
- Water solubility:
- 860 g/L
- at the temperature of:
- 20 °C
Additional information
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