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EC number: 700-989-5 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity to aquatic invertebrates:
Results from short-term invertebrate toxicity studies with several invertebrate species on an analog substance suggest that DIUP does not cause toxicity at the maximum achievable aqueous concentrations investigated in these tests (i.e. in excess of water solubility).
Key value for chemical safety assessment
Additional information
The results of short-term toxicity studies are reported as EC50, LC50, and NOEC values for acute invertebrate toxicity. The NOEC values represent the highest concentration measured in these studies that did not demonstrate effects. In all cases this was the highest concentration attainable and measured under the conditions of the study. The use of the NOEC values in the results overview table to derive values for quantitative risk assessment is inappropriate as they are not true NOEC values.
I5 Summary
The data used to characterize the invertebrate acute toxicity of diisoundecyl phthalate (DIUP; CAS #85507 -79 -5) ester are consistent with the data for several high molecular weight phthalate diesters summarized by Staples et al. (1997). These data show that high molecular weight phthalate diesters do not produce acute toxicity to invertebrates at or below their maximum attainable solubliity. These data suggest that DIUP will also not produce invertebrate acute toxicity. The data used to characterize DIUP are for diundecyl phthalate (DUP; CAS #3648 -20 -2) ester, which is an analog to DIUP. Both DIUP and DUP contain undecyl alkyl groups. Whereas DUP contains linear undecyl alkyl groups, the alkyl groups in DIUP are branched. Therefore, because of the structural similarity between these substances and the similar biological behavior of high molecular weight phthalate esters in general, data for the analog can be used to characterize the biological effects of DIUP for this endpoint. The acute invertebrate dataset includes results for three species, Daphnia magna, Paratanytarsus parthenogenetica, and Mysidopsis bahia (new name: Americamysis bahia).
Staples et al. (1997). Aquatic toxicity of eighteen phthalate esters. Environ. Toxicol. Chem. 16(5): 875 -891.
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