Registration Dossier

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature source.

Data source

Reference
Reference Type:
review article or handbook
Title:
3-hexen-1-ol, (3Z)-; Exemption from the requirement of a tolerance
Author:
Anon
Year:
2005
Bibliographic source:
Federal Register. 70 (104): 31359-31365
Report date:
2005

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified
Test type:
other: No data

Test material

Constituent 1
Chemical structure
Reference substance name:
cis-hex-3-en-1-ol
EC Number:
213-192-8
EC Name:
cis-hex-3-en-1-ol
Cas Number:
928-96-1
Molecular formula:
C6H12O
IUPAC Name:
(3Z)-hex-3-en-1-ol
Details on test material:
- Name of test material (as cited in study report): cis-3-hexen-1-ol, leaf alcohol, 3-hexen-1-ol,(3Z)
- Physical state: liquid

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No data

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Details on dermal exposure:
No data
Duration of exposure:
No data
Doses:
No data
No. of animals per sex per dose:
No data
Control animals:
not specified
Details on study design:
No data
Statistics:
No data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
No data
Clinical signs:
No data
Body weight:
No data
Gross pathology:
No data
Other findings:
No data

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The test substance was assessed for acute toxicity via the dermal route and was found to have an LD50 of >5000 mg/kg. As such, the test substance is not considered to be acutely toxic by the dermal route.