Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on developmental toxicity

Description of key information
The oral NOAEL is found to be 200 mg/kg bw/day
Effect on developmental toxicity: via oral route
Dose descriptor:
NOAEL
200 mg/kg bw/day
Additional information

One study is available from the migrated NONs files provided by ECHA. This study is found to be fairly unreliable, as there is no data provided on whether the study has been undertaken according to GLP standards, or if a guideline was followed. However, the result has been taken as valid as this is an available study, and the desire is to not repeat animal tests.

The oral NOAEL for N-(n-octyl)-2-pyrrolidinone is therefore found to be 200 mg/kg bw/day.

Justification for classification or non-classification

Additional information