Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification, but validity of model and reliability of prediction considered adequate based on a generally acknowledged source
Justification for type of information:
See EpiSuite report (attached).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
EPI (Estimation Programs Interface) Suite estimates a range of physicochemical properties, environmental fate parameters and ecotoxicity. It has been developed by the US EPA in collaboration with Syracuse Research Corporation (SRC) and is used widely by governmental and industry organisations to support the assessment of new and existing industrial chemicals
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.162 L/kg
Basis:
whole body w.w.
Remarks on result:
other: QSAR prediction

Applicant's summary and conclusion

Conclusions:
Bioconcentration factor (BCF) is predicted to be 3.162 L/kg wet weight (Log BCF 0.50) (EpiSuite BCFBAF v3.01)
Executive summary:

Bioconcentration factor (BCF) for the relevant azo portion of the registered substance is predicted to be 3.162 L/kg wet weight (Log BCF 0.50) (EpiSuite BCFBAF v3.01)