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EC number: 204-428-0 | CAS number: 120-82-1
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213 °C
- Remarks on result:
- other: Atmospheric pressure was not reported
- Executive summary:
Roempp, 2009
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213.5 °C
- Atm. press.:
- 101.3 kPa
- Executive summary:
Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006
The boiling point of 1,2,4-trichlorobenzene was reported as 213.5 °C at 1013 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213.8 °C
- Atm. press.:
- 101.3 kPa
- Executive summary:
Kirk-Othmer, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.8°C at 1013 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch scorDue to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213 °C
- Remarks on result:
- other: Atmospheric pressure was not reported.
- Executive summary:
Merck-Index, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213.5 °C
- Atm. press.:
- 1 013 hPa
- Executive summary:
Rippen, 1991, Beilstein, 1978, Dreisbach, 1995, Hann,1977, Howard, 1989, IPCS, 1991
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213.5 °C
- Atm. press.:
- 1 013 hPa
- Executive summary:
BUA/UBA, 1984
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213 - 214 °C
- Remarks on result:
- other: Atmospheric pressure was not reported.
- Executive summary:
Bolton, 1979
The boiling point of 1,2,4-Trichlorobenzene was reported between 213°C and 214 °C.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 212.9 °C
- Atm. press.:
- 1 000 hPa
- Executive summary:
Beilstein, 1978
The boiling point of 1,2,4-Trichlorobenzene was reported as 212.9 °C at 1000 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 211 °C
- Atm. press.:
- 989 hPa
- Executive summary:
Lock, 1933
The boiling point of 1,2,4-Trichlorobenzene was reported as 211°C at 989 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 213 °C
- Remarks on result:
- other: Atmospheric pressure was not reported.
- Executive summary:
Beilstein, 1878, Bender, 1972, Hommel, 1994, Hooftman, 1982, Sax, 1984, Verschueren, 1983, Ware, 1977
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 206 °C
- Remarks on result:
- other: Atmospheric pressure was not reported.
- Executive summary:
Jungfleisch, 1868
The boiling point of 1,2,4-Trichlorobenzene was reported as 206 °C.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Boiling pt.:
- 210 °C
- Remarks on result:
- other: Atmospheric pressure was not reported.
- Executive summary:
Lesimple, 1866, Noelting 1905
The boiling point of 1,2,4-Trichlorobenzene was reported as 210°C.
Referenceopen allclose all
Atmospheric pressure was not reported.
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
The boiling point of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is in the range of 213.5 °C - 213.8 °C at an atmospheric pressure of 1013 hPa. The melting point of 213.5 °C was chosen as key value for chemical safety assessment (reported by several individual references).
Roempp, 2009
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006
The Boiling point of 1,2,4-trichlorobenzene was reported as 213.5 °C at 1013 hPa.
Kirk-Othmer, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.8°C at 1013 hPa.
Merck-Index, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
Rippen, 1991, Beilstein, 1978, Dreisbach, 1995, Hann,1977, Howard, 1989, IPCS, 1991
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.
BUA/UBA, 1984
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.
Bolton, 1979
The boiling point of 1,2,4-Trichlorobenzene was reported between 213°C and 214 °C.
Beilstein, 1978
The boiling point of 1,2,4-Trichlorobenzene was reported as 212.9 °C at 1000 hPa.
Lock, 1933
The boiling point of 1,2,4-Trichlorobenzene was reported as 211°C at 989 hPa
Beilstein, 1878, Bender, 1972, Hommel, 1994, Hooftman, 1982, Sax, 1984, Verschueren, 1983, Ware, 1977
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.
Jungfleisch, 1868
The boiling point of 1,2,4-Trichlorobenzene was reported as 206 °C.
Lesimple, 1866, Noelting 1905
The boiling point of 1,2,4-Trichlorobenzene was reported as 210°C.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 213.5 °C
Additional information
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
