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EC number: 600-033-6
CAS number: 1001416-18-7
The eye irritation potential of the
substance was assessed by a single application of the substance into the
lower conjunctival sac of two female and one male rabbit, strain New
Zealand White, according to OECD Guideline 405. 0.1 ml of test substance
was applied. Occular reactions were assessed 1, 24, 48, 72 hours and 7
days after application of the substance.
Systemic toxic symptoms after
application were not observed at any time during the study. Body weight
development was within normal ranges.
All three animals showed showed a
minor occular reaction (conjunctivae redness 1 score, conjunctivae
chemosis 1 score) 1 hour after application of the substance. At 24 hours
after the application not any effect of the substance toward the eye
could be observed.
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