Registration Dossier

Administrative data

Description of key information

Skin irritation: not irritating (in vitro“Interleukin-1α”, GLP)
Eye irritation: not irritating ( in vitro “HET-CAM”)

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Justification for classification or non-classification

The test method based on the EPISKIN™ assay allows the prediction of both irritant and non-irritant substances and can thus be considered as a stand alone method to be used as replacement for the animal test. Therefore, allyl heptanoate is considered not to have skin irritatiting properties and should not be classified and labelled according to regulation (EC) No.: 1272/2008.

According to the in vitro eye irritation testing the test substance should not be classified and labelled according to regulation (EC) No.: 1272/2008.