Registration Dossier

Environmental fate & pathways

Biodegradation in soil

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Administrative data

Endpoint:
biodegradation in soil
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study uses unrealistic amounts of tetrahydrofuran that are unlikely to be present in the environment. The test material used was a combination of tetrahydrofuran and 1,4-dioxane.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Biodegradation in soil microcosms
GLP compliance:
not specified
Test type:
laboratory

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
Tetrahydrofuran and 1,4-dioxane (purities of either substance were not given).
Radiolabelling:
no

Study design

Oxygen conditions:
aerobic
Soil classification:
not specified
Details on soil characteristics:
Soil used was previously exposed to 1,4-dioxane
Duration of test (contact time)
Soil No.:
#1
Duration:
100 d
Initial test substance concentration
Soil No.:
#1
Initial conc.:
200 other: mg/l
Based on:
test mat.
Parameter followed for biodegradation estimation:
DOC removal
Details on experimental conditions:
Study was conducted at 35 °C in the dark.

Results and discussion

% Degradation
Soil No.:
#1
% Degr.:
100
Parameter:
test mat. analysis
Sampling time:
100 d
Transformation products:
not specified
Evaporation of parent compound:
not specified
Volatile metabolites:
not specified
Residues:
not specified

Applicant's summary and conclusion

Conclusions:
Under the conditions of this study, complete biodegradation of tetrahydrofuran and 1,4-dioxane occurs under enhanced conditions (35 °C and addition of nitrogen, phosphorus and other trace elements). Under ambient conditions, there was no biodegradation of tetrahydrofuran and 1,4-dioxane.