Registration Dossier
Registration Dossier
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EC number: 201-497-9 | CAS number: 83-73-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- Iodoquinol associated seizures and radiopacity.
- Author:
- Fisher AK, Walter FG, Szabo S.
- Year:
- 1 993
- Bibliographic source:
- Clinical Toxicology, 1993, Vol. 31, No. 1 : Pages 113-120
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: not available
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- Diiodohydroxyquinoline
- EC Number:
- 201-497-9
- EC Name:
- Diiodohydroxyquinoline
- Cas Number:
- 83-73-8
- Molecular formula:
- C9H5I2NO
- IUPAC Name:
- 5,7-diiodoquinolin-8-ol
Constituent 1
Test animals
- Species:
- other: Human child
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- intervals of 13 Days
- Doses:
- 819 mg/kg/13 Days
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LDLo
- Effect level:
- 819 mg/kg bw
- Clinical signs:
- other: no data
- Gross pathology:
- no data
- Other findings:
- no data
Any other information on results incl. tables
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Blood - oxidant related (GPD deficient) anemia
Applicant's summary and conclusion
- Interpretation of results:
- other: not specified
- Remarks:
- Criteria used for interpretation of results: not specified
- Conclusions:
- Acute toxicity by Oral route examined at dose concentration 819 mg/kg bw
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