1,1-dimethoxytrimethylamine

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study well documented, meets generally accepted scientific principles, acceptable for assessment.

Data source

Reference

Reference Type:

publication

Title:

Results of the harmful effects of selected water pollutants (anilines, phenols, aliphatic compounds) to Daphnia magna.

Author:

Kuehn, R. et al.

Year:

1989

Bibliographic source:

Water Research 23(4): 495-499

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN 38412 Teil 11

Principles of method if other than guideline:

German DIN guideline: "Bestimmung der Wirkung von Wasserinhaltsstoffen auf Kleinkrebse. Determination of the effects of substances in water to small crustacea

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Methanol

EC Number:

200-659-6

EC Name:

Methanol

Cas Number:

67-56-1

IUPAC Name:

methanol

Details on test material:

- Name of test material (as cited in study report): Methanol
- Analytical purity: no data

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

TEST ORGANISM
- Common name: water flea
- Age at study initiation (mean and range, SD): 6 - 24 h
- Feeding during test: No feed was given during the test period.

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Hardness:

total hardness: 2.4 mmol/L
Calcium to magnesium ratio: 4:1
Sodium to potassium ratio: 10:1

Test temperature:

20°C

pH:

initial 8.0 ± 0.2

Dissolved oxygen:

≥ 2 mg/L

Details on test conditions:

TEST SYSTEM
- Test vessel: 50 mL beakers

- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2



TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: From the solution with the pollutant, dilution series were prepared using dilution water of the specified composition. The concentration steps of the test solution were selected so as to give 3-4 EC values in a range between EC0 and EC100, of which at least one value was below and one above EC50.

- acid capacity: 0.8 mmol/L

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

EC0

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 2

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 3

Duration:

24 h

Dose descriptor:

EC0

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 4

Duration:

24 h

Dose descriptor:

EC50

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility