Registration Dossier
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EC number: 200-087-7 | CAS number: 51-28-5
Endpoint summary
Administrative data
Description of key information
Additional information
WATER COMPARTMENT
In water compartment estimated and experimental BCF values are available for 2,4-dinitrophenol.
The overall range of BCF measured in salt water is from 3.0 to 16 (EPA databank). Additional studies measured BCF values of < 0.4-0.7 and <3.7.
According to a classification scheme these BCFs suggest that the potential for bioconcentration in aquatic organisms for 2,4 -dinitrophenol is low (SRC) (NITE; Chemical Risk Information Platform (CHRIP)). Using the equation log BCF = 1.02xlogKow - 1.82 to correct the BCF due to ionization in water and a value of 1.54 for log Kow, the BCF of 2,4-DNP in fish can be estimated to be 0.56. Therefore, the concentration of 2,4-DNP in fish may be even lower than its concentration in water. (McCarty LS, Mackay D, Smith AD, et al. 1993). Furthermore, bioconcentration of dinitrophenols from water to aquatic organisms and from soil to plants is not expected to be important. No data were located on the biomagnification potential for dinitrophenols in predators that consume contaminated prey (EPA 1986a; O’Connor et al. 1990).
SOIL COMPARTMENT
Some loss of dinitrophenols from soil could occur by plant uptake. At concentrations likely to cause maximum bioaccumulation (10 mg/kg), the bioaccumulation factor (concentration in plant over concentration in soil) in lettuce, carrot (tops, peels, and root), hot pepper foliage, and fruits was <0.01 at a soil pH of 6.7-7.2.
Since dinitrophenols undergo metabolism in plants, plant accumulation of dinitrophenols due to uptake would not be significant. Since the concentration of the non-ionized form is only <0.25% of total DNP at pH 6.7, the soil pH has to be considerably lower for uptake to be significant in plants (O’Connor GA, Lujan JR, Jin Y. 1990)
Infact, in a Shea PJ, Weber JB, Overcash MR. 1983 study it has been demonstrated that the uptake and the translocation could be significant in soil with low pH where the concentration of non-ionized dinitrophenols (more readily adsorbed than the ionized form) are higher.
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