Registration Dossier
Registration Dossier
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EC number: 629-767-5 | CAS number: 1228186-18-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.037 mg/L
- EC10 or NOEC for freshwater algae:
- 0.011 mg/L
Additional information
Exponentially growing P. subcapitata was exposed to the test material at nominal concentrations of 0, 20, 40, 90, 210, 450 and 1000 µg/L in a static 72 -hour toxicity test. The biomass in the control culture increased exponentially by a factor greater than 16 within the 72-hour test period. The test design included an untreated control comprising untreated algal growth medium only, and an uninoculated blank containing only dilution water. However the test item concentration was not maintained within the designated limit of 80% from the start concentration
The 72 -hour ErC50 (growth rate) and EbC50 (integrated biomass) endpoints determined by probit analysis for P. subcapitata exposed to the test material under static conditions were were 0.037 and 0.016 mg/L respectively. The corresponding 72 -hour NOECs based on inhibition of specific growth rate and integrated biomass were both 0.011 mg/L respectively.
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