Registration Dossier
Registration Dossier
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EC number: 211-059-9 | CAS number: 628-89-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Journal of Industrial Hygiene and Toxicology.
- Author:
- JIHTAB
- Year:
- 1 944
- Bibliographic source:
- Journal of Industrial Hygiene and Toxicology. 26 (1944), 269.
- Reference Type:
- review article or handbook
- Title:
- DPIM : DKN000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials); Journal of Industrial Hygiene and Toxicology. 26 (1944), 269.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from SAX
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- 2-(2-chloroethoxy)ethanol
- EC Number:
- 211-059-9
- EC Name:
- 2-(2-chloroethoxy)ethanol
- Cas Number:
- 628-89-7
- Molecular formula:
- C4H9ClO2
- IUPAC Name:
- 2-(2-chloroethoxy)ethan-1-ol
- Details on test material:
- - Name of test material : 2-(2-chloroethoxy)ethanol
- Molecular formula : C4H9ClO2
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: other details not available
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Acute dermal toxicity (LD50) of 2-(2-chloroethoxy)ethanol in guinea pig was found to be 3000 mg/Kg. This value indicates that 2-(2-chloroethoxy)ethanol is not toxic to skin of guinea pig
- Executive summary:
Acute dermal toxicity (LD50) of 2-(2-chloroethoxy)ethanol in guinea pig was found to be 3000 mg/Kg. This value suggests that 2-(2-chloroethoxy) ethanol is not toxic to skin of guinea pig. In order to classify the substance in dermal category the lethal dose should be in the range of less than 2000 mg/kg in normal condition.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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