Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-059-9 | CAS number: 628-89-7
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The substance, 2-(2-chloroethoxy) ethanol , do not have a bioaccumulation potential based on estiamtion results supported by the facts of physicochemical parameters and persistant nature of the substance.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Adsorption:
The absorption capacity of 2-(2-chloroethoxy) ethanol is low (as has been stated section 5.4.1 of the dossier), which is also supported by the fact that the bioaccumulation factor for the substance is much lower and so even after the exposure the absorption capability will be less in this case.
Distribution:
In case the substance, 2-(2-chloroethoxy) ethanol, is absorbed (though in small quantity) it will not be accumulated in the body. This is supported by the fact that the substance have not only low BCF value (as mentioned in section 5.3.1 of the same dossier) but also have a moderate level of Kow which will support the reasoning that though the substance will enter the body but will get distributed through the lipid in the body.
Excretion:
Further to this distribution after the absorption process, the excretion process through urine would be faster as the molecular weight of the substance, 2-(2-chloroethoxy) ethanol, is > 300 and this is a favourable value for excretion via the urine route.
Dermal Absorption relation :
In case the substance,2-(2-chloroethoxy) ethanol, is absorbed (though in small quantity) it will not be accumulated in the body. This is supported by the fact that the substance have not only low BCF value but alos have a moderate level of Kow which will support the reasoning that though the substance will enter the body but will get distributed through the lipid in the body.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
