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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).

The estimated bioconcentration factor (BCF) for 5-nitrosalicylic acid is 3.2, which does not exceeds the EPA bioconcentration criteria (>= 1,000). Thus, it is concluded that 5-nitrosalicylic acid is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.

Key value for chemical safety assessment

BCF (aquatic species):
3.2 dimensionless

Additional information

No. of studies of target substance 5-nitrosalicylic acid reviewed for bioaccumulation from reliable sources having Klimisch rating 2.

 

The summary of the results are presented below

 

 

Sr.No

Endpoint

Value

result

Sources

1

BCF

3.2

Non-bioaccumulative

Predicted data from PBT profiler

2

BCF

2.897 L/Kg

Non-bioaccumulative

Predicted data from QSAR

3

BCF

3.1622 L/Kg

Non-bioaccumulative

Predicted data from Vega QSAR

 

By applying weight of evidence approach the target chemical 5-nitrosalicylic acid found to be non bioaccumulative with BCF value2.897 L/Kg3.2 L/Kg whichis not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.