Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Biodegradation in water :

No. of studies of target substance 5-nitrosalicylic acid reviewed for Biodegradation in water: screening tests from reliable sources having Klimisch rating 2.

 

The summary of the results are presented below

 

 

Sr.No

Endpoint

Half life

Parameter

Sources

1

ready biodegradability

50% degradation in 15 days

Test mat. analysis

Predicted data from PBT profiler

2

ready biodegradability

51.66% degradation

O2 consumption

Predicted data from QSAR

 

 

By applying weight of evidence approach the target chemical found to be readily biodegradable with 50% to 51.66% percentage degradation.Thus it is concluded that 5-nitrosalicylic acid is biodegradable in water.

Biodegradation in water and sediment :

Based on the Level III Fugacity Model, the half life period of the 5-nitrosalicylic acid was estimated. The half period of 5-nitrosalicylic acid in water is 15 days (360 hrs) therefore it is considered that the substance will qualify as not persistent as the half life does not exceed the EPA criteria of 60 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 140 days (3360 hrs).

Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that 5-nitrosalicylic acid does not diffuse in the sediment medium since it's percentage in the sediment medium is reported to be 0% and hence persistence in the sediment compartment is not likely to be critical. 

Media

Half-Life (days)

Percent in
Each Medium

Water

15

  24%

Sediment

140

  0%

Biodegradation in soil :

No. of studies of target substance 5-nitrosalicylic acid reviewed for Biodegradation in soil from reliable sources having Klimisch rating 2.

 

The summary of the results are presented below

 

Sr.No

Endpoint

Half life

Parameter

result

Sources

1

ready biodegradability

30days

Test mat. analysis

biodegradable

Predicted data from PBT profiler and EPI suite

2

ready biodegradability

28.399 days

DT50(Dissipation time)

biodegradable

Predicted data from QSAR

 

 

By applying weight of evidence approach the target chemical found to be readily biodegradable with half life 28.399 to 30 days. does not exceeds the threshold (60 days) of being persistent in soil Thus it is concluded that 5-nitrosalicylic acid is biodegradable in soil.