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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Key data: EC50(72 h) = 16.0 mg/L (growth rate); EC10(72h) = 2.19 mg/L (growth rate); NOEC(72 h) = 3.20 mg/L  (growth rate); LOEC(72 h) = 10.0 mg/L (growth rate)
(All effect levels are given based on nominal test item concentrations).

Key value for chemical safety assessment

EC50/LC50 for freshwater algae:
16 mg/L
EC10, LC10 or NOEC for freshwater algae:
3.2 mg/L

Additional information

The toxicity test to aquatic algae (Scheerbaum 2012) performed according to EU Method C.3., OECD 201 and GLP was rated with RL=1 (reliable without restrictions) and used as a key study.

The results indicate that the test item inhibits the growth of the freshwater green alga Pseudokirchneriella subcapitatus after 72 hours with the following effect values (nominal test item concentrations) (measured concentrations within 80 - 120% of nominal values):

The EC50-values with 95 % confidence intervals for inhibition of specific growth rate (ErC50) and yield (EyC50) after 72 hours were 16.0 (13.6 – 18.9) mg test item/L and 3.31 (1.80 – 5.75) mg test item/L, respectively.

The NOEC-values for the inhibition of specific growth rate and yield after 72 hours were 3.20 and < 1.00 mg test item/L, respectively.