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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

NOEC: 0.3 mg/L

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.3 mg/L

Additional information

The phthalate esters are1,2-benzenedicarboxylic acids with side chain esters ranging in carbon chain length from C1 to C13.The US EPA High Production Volume (HPV) chemical challenge program has proposed grouping phthalate esters into a single category, divided into 3 sub-categories, this based on the structural similarities of the substances and theirphysicochemical and toxicological properties. These sub-categories are: low molecular weight phthalates, transitional phthalates, and high molecular weight phthalates. The high molecular weight phthalates are defined as being produced from alcohols with straight-chain carbon backbones of >C7 or a ring structure. These include varying mixed isomers of linear and branched diheptyl, dioctyl, dinonyl, didecyl, diundecyl and ditridecyl phthalate. All have low solubility in water and are regarded as being too insoluble to exhibit acute or chronic toxicity. Read-across from closely related phthalates thus appears reasonable.

Long-term toxicity to fish of a phthalate ester with C11 chain length has been determined in a fish early life stage test with rainbow trout. Under the conditions of the test the NOEC, based on the mean measured concentration, was 0.30 mg/L, the highest concentration investigated and regarded as the maximum water solubility under the test conditions.