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Tidigare/resultat

Tidigare/resultat

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Alkenes, C20-24 alpha 700-962-8 -
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)
22/10/2013
22/10/2013
05/12/2013
05/12/2013
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 700-961-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Reaction mass of butane-2,2-diyl dihydroperoxide and di-sec-butylhexaoxidane 700-954-4 1338-23-4 Sub-chronic toxicity (90-day): oral 19/12/2013 03/02/2014
Alkane-alpha,omega-diyl bis{[(trimethoxysilyl)propyl]carbamate}_M2 700-904-1 1350725-68-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl [3-(trimethoxysilyl) propyl]carbamate CAS 23432-62-4 02/11/2018 17/12/2018
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons 700-762-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
25/09/2012
25/09/2012
12/11/2012
12/11/2012
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons 700-762-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with an analogue substance.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
01/10/2018
01/10/2018
01/10/2018
15/11/2018
15/11/2018
15/11/2018
Destillation fraction of chlorosilanes 700-717-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation 
16/05/2012
16/05/2012
02/07/2012
02/07/2012
Trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide 700-597-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/06/2012
18/06/2012
02/08/2012
02/08/2012
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes 700-497-0 -
Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/11/2010
25/06/2012
03/01/2011
09/08/2012
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol 700-427-9 -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
01/12/2010
01/12/2010
01/12/2010
17/01/2011
17/01/2011
17/01/2011
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate 700-316-5 -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-days): oral
11/01/2011
11/01/2011
25/02/2011
25/02/2011
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide 700-208-8 - Sub-chronic toxicity (90-day): oral 04/10/2018 19/11/2018
3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate 700-071-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
02/07/2012
02/07/2012
2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid 700-002-8 - Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012
hexahydrophthalic acid diglycidylester 696-026-0 1395383-69-3 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014
Hexadecyldimethylamine 695-101-5 1275611-65-8 Reproductive toxicity (pre-natal developmental toxicity) 23/04/2018 07/06/2018
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol 692-731-2 76950-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate 642-902-2 163802-53-7 Genetic toxicity in vivo 10/03/2017 25/04/2017
Alcohols, C18-22, distn. residues 641-136-6 -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Alcohols, C18-22, distn. residues 641-136-6 1160164-88-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid 641-088-6 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane 640-964-5 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
(E)-2-benzylideneoctanal 639-566-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Amides, Fatty acids C18 unsaturated, reaction products with tetraethylenepentamine 630-459-8 1225197-81-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
N-[2-(piperazin-1-yl)ethyl]C18-unsatured-alkylamide 629-767-5 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Fatty acids C18 unsat, reaction products with triethylenetetramine 629-765-4 1226892-44-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
potassium 4-cumenesulfonate 629-764-9 164524-02-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate  
22/06/2017
22/06/2017
07/08/2017
07/08/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
potassium 4-isopropylbenzenesulphonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015
Fatty acids, C18 unsaturated, reaction product with ammonia-ethanolamine reaction by-products 629-757-0 1224966-15-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Fatty acids C18 unsat, reaction products with polyethylene amines 629-742-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Amides, fatty acids C18 unsat, reaction products with polyethylene amines 629-735-0 1226892-50-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Fatty acids C18 unsat, reaction products with Pentaethylenehexamine 629-732-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Fatty acids C18 unsat, reaction products with tetraethylenepentamine 629-725-6 1226892-45-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
N-(C16-C18)alkyl(C16-C18)alkane-1-amine 629-721-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
N,N,N`,N`,N``-Pentamethyl-N-C16-18 (even numbered) C18 unsat.-alkyl-1,3-propanediammonium chloride 629-716-7 1211950-04-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Fatty acids, C18 unsat, reaction products with diethylenetriamine 629-715-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine 628-863-4 1219458-14-6 Reproductive toxicity (pre-natal developmental toxicity) 24/01/2019 11/03/2019
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine 628-863-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
N-(3-aminopropyl)-N`-[3-(C16-18 (evennumbered), C18 unsaturated alkyl amino)propyl]propane-1,3-diamine 628-862-9 1219458-11-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
2,6,10-trimethyldodecane 622-542-2 3891-98-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol 620-540-6 1218787-32-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9 14/03/2016 28/04/2016
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] 620-097-9 54299-17-1
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
22/11/2017
22/11/2017
08/01/2018
08/01/2018
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane 618-939-5 933999-84-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane 618-939-5 933999-84-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): dermal
18/11/2014
18/11/2014
18/11/2014
02/01/2015
02/01/2015
02/01/2015
Renewable hydrocarbons (diesel type fraction) 618-882-6 928771-01-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal 616-248-3 75627-31-5
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Reaction products of a polyol of pentaerythritol and propylene oxide, epichlorohydrin and hydrogen sulfide 615-735-8 72244-98-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017



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