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Tidigare/resultat

Tidigare/resultat

Tidigare/resultat

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
Search for chemicals

 

There are currently no ongoing consultations.
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Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine 264-438-6 63738-22-7 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant. 		27/01/2020 12/03/2020 Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
 Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
 Details
2-[[(butylamino)carbonyl]oxy]ethyl acrylate 264-036-0 63225-53-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020 Details
Tris[4-(diethylamino)phenyl]methylium acetate 263-974-8 63157-72-2 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2011 29/08/2011 Details
Methyl 4-[[(2,5-dichlorophenyl)amino]carbonyl]-2-[[2-hydroxy-3-[[(2-methoxyphenyl)amino]carbonyl]-1-naphthyl]azo]benzoate – bulk and nano forms 263-272-1 61847-48-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 03/10/2023 17/11/2023 Details
1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-nortall-oil alkyl derivs. 263-171-2 61791-39-7 Bioaccumulation aquatic / sediment 16/05/2014 30/06/2014 Details
Fatty acids, tall-oil, compds. with diethanolamine 263-157-6 61790-66-7 Sub-chronic toxicity (90-day): oral||Note: testing proposed with Amides, C8-18 (even numbered) and C18-unsatd., N-(2-hydroxypropyl)  (EC no. 931-329-6) 03/05/2023 19/06/2023 Details
Resin acids and Rosin acids, sodium salts 263-144-5 61790-51-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, sodium salts 263-144-5 61790-51-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, potassium salts 263-142-4 61790-50-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, potassium salts 263-142-4 61790-50-9
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt 262-872-0 61617-00-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane 262-061-1 60111-54-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
 Details
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate 261-879-6 59719-67-4 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate 261-879-6 59719-67-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate 261-665-2 59219-71-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
 Details
(ethoxymethoxy)cyclododecane 261-332-1 58567-11-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
3,5,5-trimethylhexyl acetate 261-245-9 58430-94-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
Ethyl 4-[[(methylphenylamino)methylene]amino]benzoate 260-976-0 57834-33-0 Genetic toxicity in vivo 10/05/2022 27/06/2022 Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
 Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
 Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
 Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2021 15/11/2021 Details
1,3,3-trimethyl-N-(2-methylpropylidene)-5-[(2-methylpropylidene)amino]cyclohexanemethylamine 259-393-4 54914-37-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 21/03/2014 05/05/2014 Details
Vinyl neononanoate 259-160-7 54423-67-5 Sub-chronic toxicity (90 day): oral 16/05/2012 02/07/2012 Details
Zinc bis[bis(dodecylphenyl)] bis(dithiophosphate) 259-048-8 54261-67-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
19/11/2018
19/11/2018

Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
12/12/2014
12/12/2014
26/01/2015
26/01/2015
 Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1 Long-term toxicity to fish
Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. 		31/08/2015 15/10/2015 Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione 258-904-8 53988-10-6
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
Sodium 2,4,5-trichlorobenzenesulphonate 258-548-3 53423-65-7 Genetic toxicity in vivo 30/09/2021 15/11/2021 Details
Sodium O,O-diisobutyl dithiophosphate 258-508-5 53378-51-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
 Details
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
 Details
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate 258-053-2 52628-03-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
 Details
Sodium 3-(allyloxy)-2-hydroxypropanesulphonate 258-004-5 52556-42-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
 Details
1,3,5-tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 257-913-4 52434-90-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
 Details
3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile 257-884-8 52372-36-8 Genetic toxicity in vivo 26/10/2022 12/12/2022 Details
N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diallylamino)-4-methoxyphenyl]acetamide 257-486-4 51868-46-3 Genetic toxicity in vivo 26/10/2022 12/12/2022 Details
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: testing proposed with dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) (EC 268-717-3) 21/12/2021 04/02/2022 Details
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Details
3,7-dimethyloct-6-enenitrile 257-288-8 51566-62-2 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
2-(2-Ethoxyethoxy)-2-methylpropanee 257-196-8 51422-54-9 Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant 01/09/2017 16/10/2017 Details
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