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Tidigare/resultat

Tidigare/resultat

Tidigare/resultat

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
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There are currently no ongoing consultations.
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Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
4-(4-isopropoxyphenylsulfonyl)phenol 405-520-5 95235-30-6 Reproductive toxicity (pre-natal developmental toxicity) 24/08/2020 08/10/2020 Details
Alkanoic acid and polyoxomolybdate borate alkanoate clusters 944-813-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Bisisopropyl peroxydicarbonate 203-317-4 105-64-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate 931-536-1 - Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Gas oils (petroleum), light vacuum 265-059-9 64741-58-8
Sub-chronic toxicity (90-day): oral
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Distillates (petroleum), light hydrocracked 265-078-2 64741-77-1
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Fuel oil, no. 2 270-671-4 68476-30-2
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Fuel oil, no. 4 270-673-5 68476-31-3
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum, (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Fuels, diesel, no. 2 270-676-1 68476-34-6
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Gas oils (petroleum), hydrodesulfurized light vacuum 265-190-1 64742-87-6
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with category members - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) 1st (Rat) and 2nd species (Rabbit) (Dermal route) || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Fuels, diesel 269-822-7 68334-30-5
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Cobalt, borate 2-ethylhexanoate complexes 295-032-7 91782-60-4
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
 Details
Triethoxyhexadecylsilane 240-465-9 16415-13-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
 Details
[3-(trimethoxysilyl)propyl]urea 245-904-8 23843-64-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020 Details
Bis(triethoxysilylpropyl)amine 236-818-1 13497-18-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Bis(trimethoxysilylpropyl)amine (EC 403-480-3) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020 Details
Polyamide wax 434-430-9 - Long-term toxicity to fish 07/07/2020 21/08/2020 Details
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
 Details
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 241-881-3 17955-88-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
Bis(trimethoxysilylpropyl)amine 280-084-5 82985-35-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
dodecamethylpentasiloxane 205-492-2 141-63-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-8 15545-97-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020 Details
3,4-dihydroxybenzonitrile 241-367-9 17345-61-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Barium sulfate 231-784-4 7727-43-7 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1) 17/06/2020 03/08/2020 Details
Citronellyl formate 203-338-9 105-85-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Dimethyl 2,2'-azobis(2-methylpropionate) 219-976-6 2589-57-3 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Linalyl acetate 204-116-4 115-95-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/06/2020 03/08/2020 Details
Maleic acid 203-742-5 110-16-7 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020 Details
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate 247-161-5 25646-71-3 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
N-acetylhexanelactam 217-565-6 1888-91-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Potassium 3-sulphonatopropyl acrylate 250-465-0 31098-20-1 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Potassium dicyanoargentate 208-047-0 506-61-6 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Potassium dicyanoaurate 237-748-4 13967-50-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 911-381-6 - Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride 947-115-0 - Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
1-ethoxy-2-(2-methoxyethoxy)ethane 213-690-5 1002-67-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
25/05/2020
09/07/2020
09/07/2020
09/07/2020
 Details
1,4-dimethylpiperazine 203-412-0 106-58-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer 234-293-3 11071-15-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
(R)-p-mentha-1,8-diene 227-813-5 5989-27-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 701-339-3 - Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020 Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
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