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EC number: 827-772-9 | CAS number: 20650-07-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (3-methoxypropyl)dimethylamine
- EC Number:
- 827-772-9
- Cas Number:
- 20650-07-1
- Molecular formula:
- C6H15NO
- IUPAC Name:
- (3-methoxypropyl)dimethylamine
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- A fresh sample of activated sludge was collected from the aeration tank of the Zhu Yuan Domestic Wastewater Treatment Plant in Shanghai which treats predominantly domestic sewage with Anaerobic-Oxic process(A/O). The activated sludge was kept by aeration until used. The sludge was washed with mineral medium. After centrifugation, the supernatant was decanted. This procedure was repeated three times(4000 rpm, 4°C, centrifuge 20 minutes). Then, the concentrated sludge was weighed, dried at 105°C for 1 h. The final concentration of the activated sludge in the test medium was 30mg/L.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 22 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- without nitrification: ThOD(NH3) of DMMOPA = 2.32mg O2/mg.
Since the percentage biodegradation in the Day 28 was <10%, no correction for the oxygen consumed by nitrification of nitrite and nitrate was performed. ThODNH3 was used for calculation.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4
- Sampling time:
- 28 d
- Remarks on result:
- other: assuming no nitrification
BOD5 / COD results
- Results with reference substance:
- In the reference control, biodegradation of sodium benzoate reached 84% and 88% within 14 and 28 days of exposure, resp.
In the toxicity control with 22 mg/L DMMOPA, biodegradation of sodium benzoate reached 61% and 67% within 14 and 28 days of exposure, resp.
Therefore, the test substance was considered not to have a significant toxic or inhibitory effect on the activity of the microbial inoculum.
Any other information on results incl. tables
10-day window: not applicable as no noteworthy biodegradation took place.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Executive summary:
The test substance did not show noteworthy biodegradation (was not readily biodegradable) over 28 days in OECD 301F protocol.
As the reference substance sodium benzoate was readily biodegradable in the toxicity control experiment with 22 mg/L DMMOPA, DMMOPA did not have a significant toxic or inhibitory effect on the activity of the microbial inoculum.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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