Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-548-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 days
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- OECD Guidelines for Testing of Chemicals 301B Ready Biodegradability: CO2 Evolution test 1992
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Identification: ColaLiquid DC-5
Lot/batch number: 53467J16
Homogeneity (supplied): Homogeneous
Homogeneity (observed): Homogeneous
Date of receipt: 12 December 2016
Expiry date: 3/8/2018
Purity/Composition of test substance: CAS Number: 68855-69-6
Cocamide diisopropanolamine 84-88%
Glycerin 5-8%
Free Amine (DIPA) <5%
Chemex reference: ECO161203
Required storage conditions: Ambient (15°C ±10°C) - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Source: Cambridge Sewage Treatment Works, Cowley Road
Date of collection: 21/02/17 - Duration of test (contact time):
- 28 d
- Details on study design:
- 0.0105g of ColaLiquid DC-5 was dissolved in 100 ml deionised water and analysis was performed in triplicate.
Deionised water and bracketing standards (blank, 20ppm and 75ppm TOC std) were also tested (triplicate). - Reference substance:
- acetic acid, sodium salt
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 39
- Sampling time:
- 9 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- >= 71 - <= 74
- Sampling time:
- 28 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 84
- Sampling time:
- 29 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- ColaLiquid DC-5 achieved significant biodegradation over the 28 day period with a maximum of 84% recorded on day 29. This exceeds the >60% degradation relative to the ThCO2 value required for a pass. However, the test protocol also requires that a 10-day window is applied to the degradation results (60% degradation to be reached within 10 days of 10% of the theoretical ThCO2). This was not achieved (10% reached around day 5 and 60% achieved around day 19),
therefore ColaLiquid DC-5 failed to achieve a pass according to the guideline.
However, because of the stringency of the test, this does not necessarily mean that the test substance is not biodegradable under environmental conditions, but indicates that more work would be necessary to establish biodegradability.
Reference
The inoculum blank should not normally produce more than 40mg/l CO2 (10.9mg/l C) for the test to be valid. A value of 39.3mg/l CO2 (10.7mg/l C) was recorded.
The toxicity control shows a drop in the rate of degradation around day 7 (see figure 1), this is most likely due to a drop in airflow through this vessel. The rate of degradation picks up after day 7 following the restoration of flow rate. The toxicity control is only relevant if low degradation is achieved by the test chemical. ColaLiquid DC-5 showed considerable degradation therefore toxicity control data is irrelevant in this study.
Description of key information
ColaLiquid DC-5 achieved significant biodegradation over the 28 day period with a maximum of 84% recorded on day 29. This exceeds the >60% degradation relative to the ThCO2 value required for a pass. However, the test protocol also requires that a 10-day window is applied to the degradation results (60% degradation to be reached within 10 days of 10% of the theoretical ThCO2). This was not achieved (10% reached around day 5 and 60% achieved around day 19), therefore ColaLiquid DC-5 failed to achieve a pass according to the guideline
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.