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Diss Factsheets
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EC number: 947-548-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Reason / purpose for cross-reference:
- assessment report
- Reason / purpose for cross-reference:
- assessment report
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- The water solubility of Cocamide DIPA was attempted to be measured according to OECD test method TG 105, but was unable to be measured due to the physical properties of the mixture in that it was apparent that some constituents of the UVCB are more soluble in water than other constituents and a clear solution was difficult to obtain. After several attempts, dispersions were obtained.
- Deviations:
- yes
- Remarks:
- visual inspection of solutions and confirmation by HPLC from the ecotoxicity reports
- Principles of method if other than guideline:
- The water solubility of Cocamide DIPA was attempted to be measured according to OECD test method TG 105, but was unable to be measured due to the physical properties of the mixture in that it was apparent that some constituents of the UVCB are more soluble in water than other constituents and a clear solution was difficult to obtain. After several attempts, dispersions were obtained.
However, even when there was apparent undissolved material, it was clear that a significant part of the substance does dissolve in water. This was confirmed thy Ecotoxicity testing where a stock solution of 1000 mg/l was not clear in water, but 100 mg/l was only slightly hazy. Confirmation of dissolution was carried out by HPLC analysis
For the purposes of ecotoxicity testing, solubility was considered to be approximately 100 mg/l and was clear that a substantial part of the substance was soluble in excess of 100 mg/l. Laboratory records suggest 100 mg/l was 'virtually clear'. There was also a dose response in algae up to 100 mg/l implying that saturation is > 100 mg/l.
For purposes of the CSA and to provide a minimum figure for estimation of comparative solubilities of the substance in water and octanol, the nominal figure of 100 mg/l seems appropriate. - GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Cola®Liquid DC-5 (lot 58039G17)
- Water solubility:
- ca. 100 mg/L
- Conc. based on:
- test mat.
- Remarks on result:
- other: estimated based on information from ecotoxicity testing
- Conclusions:
- Due to the liquid surfactant nature of the Cocamide DIPA it is not possible to determine the water solubility of the substance using the standard OECD 105 test method. A result of ca 100 mg/l has been established based on the fact that for the purposes of ecotoxicity testing, solubility was considered to be approximately 100 mg/l and was clear that a substantial part of the substance was soluble in excess of 100 mg/l. Laboratory records suggest 100 mg/l was 'virtually clear'. There was also a dose response in algae up to 100 mg/l implying that saturation is > 100 mg/l. For purposes of the CSA and to provide a minimum figure for estimation of comparative solubilities of the substance in water and octanol, the nominal figure of 100 mg/l seems appropriate.
Reference
Description of key information
Due to the liquid surfactant nature of the Cocamide DIPA it is not possible to determine the water solubility of the substance using the standard OECD 105 test method. A result of ca 100 mg/l has been established based on the fact that for the purposes of ecotoxicity testing, solubility was considered to be approximately 100 mg/l and was clear that a substantial part of the substance was soluble in excess of 100 mg/l. Laboratory records suggest 100 mg/l was 'virtually clear'. There was also a dose response in algae up to 100 mg/l implying that saturation is > 100 mg/l. For purposes of the CSA and to provide a minimum figure for estimation of comparative solubilities of the substance in water and octanol, the nominal figure of 100 mg/l seems appropriate.
Key value for chemical safety assessment
- Water solubility:
- 100 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.