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EC number: 812-241-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Septembre 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. Test substance is adequately specified. Therefore full validation applies.
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes
- Remarks:
- GLP Compliance Programme (inspected on October 13 and 14 2014/ signed on April 8, 2015)
- Type of method:
- capillary method
- Key result
- Decomposition:
- yes
- Remarks:
- Signs of degradation of the substance were observed between 89.8°C (363.0 K) and 170.3°C (443.5 K)* (mean of two independent determinations). At the end of the test, the test item did not change back into the original state but remained caramelised.
- Decomp. temp.:
- >= 89.8 - <= 170.3 °C
- Remarks on result:
- other:
- Remarks:
- In the Main Test, no melting point and boiling point/range was detected.
- Conclusions:
- No melting point was recorded.
- Executive summary:
The melting point of the test substance was tested under GLP according to EU A1 and OECD 102, by capillary method. No melting point was recorded.
First, a small amount was heated in a test tube in the aluminium block. Second, the capillary tube containing the test item was set into the aluminium block with quick increase in temperature. In both Pre-Tests, signs of degradation of the substance were observed. The determination of the Main Test for the melting point was performed in duplicate. In both determinations, no melting point and boiling point/range were detected and signs of degradation of the substance were observed.
In all determinations, the test item did not change back into the original state but remained caramelised.
According to the Main Test, the degradation of the substance was observed between 90°C (363.2 K) and 170.5°C (443.7 K) (mean of two independent determinations).
Reference
Pre-Test
First Pre-Test in a test tube
First a small amount was heated in a test tube in the aluminium block in order to approximate
temperature of melting and boiling of the test item or the degradation / decomposition
of the test item.
The following observations were done:
Table 4.2/1 Observations of the Pre-Test in a test tube
Observations |
Temperature* |
Colourless condensate visible |
103.3 °C |
Test item bloated appearance like beaten eggs white with a hard dome |
136.8 °C |
Colour change visible to yellow |
154.6 °C |
Test terminated, test item looks like cappuccino with milk froth |
188.2 °C |
*All temperatures were stated without the deviation of the thermometer. Under the dome the test item is liquid.
No melting / boiling point can be approximate with the first Pre-Test, performed in a test tube. However, signs of degradation of the test item were observed. The test item did not change back into the original state at the end of the first Pre-Test (irreversible change of appearance and colour).
Second Pre-Test in a capillary
The capillary tube containing the test item was set into the aluminium block with quick increase
in temperature ( < 10K/min) in order to better apprehend the melting range or the
degradation range of the test item.
The following observations were done:
Table 4.2/2 Observations of the Pre-Test in a capillary tube
Observations |
Temperature |
Capillary set into the aluminium block |
21.5 °C |
The test item bloated upward a bit |
68.1 °C |
Test item shrivelled together, a colourless condensate was visible |
102.9 °C |
Test item bloated appearance like beaten eggs white with a hard dome |
134.9 °C |
Colour change visible to yellow |
148.7 °C |
Test item dark brown, heating plate turned off |
196.5 °C |
*All temperatures were stated without the deviation of the thermometer
In the second Pre-Test performed in a capillary tube, no melting of the substance was observed, but signs of degradation of the substance were observed. At the end of this Pre- Test, the test item did not change back into the original state but remained caramelised.
Main Test
At first, the capillary tube containing the test item was set into the block at 85.1 °C. The block was heated gently. The test item shrivelled together at 89.4 °C the test was terminated because the performance criteria were not fulfilled (The test should be started at least 10 °C below the expected melting point). A second test was performed the capillary tube containing the test item was set into the block at 75.0 °C. The test item shrivelled together at 89.9 °C. At 130.4 °C the test item bloated and appeared as yellow. As the test item colour was slightly brown and the test sample expanded up in the capillary tube at 179.6 °C the test was stopped. Unfortunately the start of the colour change was missed therefore this test was not guilty. Therefore both tests were repeated.
The capillary tube containing a fresh test item sample was then set into the aluminium block at 75.0 °C (third determination) and at 75.1 °C (fourth determination). The block was heated gently at a temperature gradient of </= 1 °C/min.
The following observations were recorded:
Table 4.2/3 Observations of the Main Test :
Observations |
First Determination* |
Second Determination* |
Capillary set into the aluminium block |
75.0 °C |
75.1 °C |
Test item shrivelled together |
89.9 °C |
90.1 °C |
Colour change visible to yellow |
118.7 °C |
117.8 °C |
expanded up in the capillary tube colour slightly brown |
151.9 °C |
150.9 °C |
Test stopped Colour brown like caramel |
167.8 °C |
173.2 °C |
* All measured values from the observations are without subtraction of the thermometer deviation
In the Main Test, no melting point and boiling point/range was detected. However, signs of degradation of the substance were observed between 90°C (363.2 K) and 170.5°C (443.7 K)* (mean of two independent determinations). At the end of the test, the test item did not change back into the original state but remained caramelised.
RESULTS AND VALIDITY
Result Test Item OF14 AT
In all performed determinations (Pre-Tests and Main Test), no melting point and boiling point/range were detected and signs of degradation of the substance were observed. In all determinations, the test item did not change back into the original state but remained caramelised. According to the Main Test, the degradation of the substance was observed between 90°C (363.2 K) and 170.5°C (443.7 K) (mean of two independent determinations).
Validity
No validity criteria could be considered as the test item decomposed.
Description of key information
No melting point was recorded
Key value for chemical safety assessment
Additional information
A fully reliable experimental study, conducted according to a recognized EU/OECD method and under GLP, is available.
No melting point was recorded but the degradation of the substance was observed between 90°C (363.2 K) and 170.5°C (443.7 K) before melting.
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