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EC number: 601-779-5 | CAS number: 121451-02-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7 July 2000 - 12 July 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from the standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to valid guidelines and conducted under GLP conditions.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0 mm Hg
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 mm Hg
- Conclusions:
- Under the conditions of the test, the vapour pressure was determined to be 7.19 E-10 Pa at 25 °C and 2.20 E-10 Pa at 20 °C.
- Executive summary:
The vapour pressure of the test material was determined in a GLP study performed according to the standardised guidelines EPA OPPTS 830.7950 and OECD 104 using the Knudsen-effusion/weight loss method.
An amount of material effusing through the opening of the cell was measured continuously with a recording microbalance working in high vacuum. The rate of weight loss of the sample (contained in a cell) through an orifice of known area and kept at an isothermal temperature was recorded and converted to the vapour pressure of the sample by calculation.
Under the conditions of the test, the vapour pressure was determined to be 7.19 E-10 Pa at 25 °C and 2.20 E-10 Pa at 20 °C.
Reference
Results
Validation of the High and Low end Capacity:
The vapour pressures of several compounds of known vapour pressure were measured using multiple orifice sizes. Since the vapour pressure for all the orifices could be fitted linearly (with error limits of ± 30 % for the high end, and a factor of 3 for the low end), it was concluded that the present setup is capable of measuring vapour pressure between 0.8 mmHG (107 Pa) and 5 x 10E-10 mmHG (6.7 x 10E-08 Pa).
Vapour Pressure Determination:
A total of 0.5 % of the starting weight of the sample was lost before the first data point in Table 1 was calculated. The total weight loss during the experiment was 2.9 %.
The vapour pressure data have been fit to the Clausius-Clapeyron equation, by a least squared method, to yield the following:
To calculate pressure in mHg
Log10 Pressure (mmHg) ± 0.05 = 18.79-8960.9/(Temperature, K)
To calculate pressure in Pa
Log10 Pressure (Pa) ± 0.05 = 20.91-8960.9/(Temperature, K)
Figure 1 shows the plot of all vapour pressure data and the fitted curve.
Table 1: Results
Temp (°C) |
Rate of Wt Loss (mg/hr) |
Orifice Size (cm) |
Clausing Factor |
Vapour Pressure |
|
torr |
Pa |
||||
90.11 |
6.31E-02 |
0.5200 |
0.882 |
1.35 E-06 |
1.80 E-04 |
92.11 |
7.54 E-02 |
0.5200 |
0.882 |
1.62 E-06 |
2.15 E-04 |
97.10 |
1.82 E-01 |
0.5200 |
0.882 |
3.94 E-06 |
5.25 E-04 |
99.09 |
2.42 E-01 |
0.5200 |
0.882 |
5.24 E-06 |
6.98 E-04 |
104.09 |
4.81 E-01 |
0.5200 |
0.882 |
1.05 E-05 |
1.40 E-03 |
105.08 |
5.55 E-01 |
0.5200 |
0.882 |
1.21 E-05 |
1.61 E-03 |
106.09 |
6.45 E-01 |
0.5200 |
0.882 |
1.41 E-05 |
1.88 E-03 |
|
|
|
|
|
|
71.14 |
8.43 E-03 |
0.9880 |
0.953 |
4.68 E-08 |
6.24 E-06 |
73.13 |
1.52 E-02 |
0.9880 |
0.953 |
8.50 E-08 |
1.13 E-05 |
78.13 |
3.18 E-02 |
0.9880 |
0.953 |
1.78 E-07 |
2.38 E-05 |
80.12 |
5.93 E-02 |
0.9880 |
0.953 |
3.34 E-07 |
4.45 E-05 |
85.12 |
1.18 E-01 |
0.9880 |
0.953 |
6.70 E-07 |
8.93 E-05 |
87.12 |
1.41 E-01 |
0.9880 |
0.953 |
8.02 E-07 |
1.07 E-04 |
Description of key information
Vapour pressure 7.19 E-10 Pa at 25 °C and 2.20 E-10 Pa at 20 °C, effusion method, EPA OPPTS 830.7950, OECD 104, Griffin 2000.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The vapour pressure of the test material was determined in a GLP study performed according to the standardised guidelines EPA OPPTS 830.7950 and OECD 104 using the Knudsen-effusion/weight loss method. The study was assigned a reliability score of 1, reliable without restrictions, in line with the principles of Klimisch et al. (1997).
An amount of material effusing through the opening of the cell is measured continuously with a recording microbalance working in high vacuum. The rate of weight loss of the sample (contained in a cell) through an orifice of known area and kept at an isothermal temperature was recorded and converted to the vapour pressure of the sample by calculation.
Under the conditions of the test, the vapour pressure was determined to be 7.19 E-10 Pa at 25 °C and 2.20 E-10 Pa at 20 °C.
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