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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 5.7
Temp.:
20 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
The test item Sa 190 elutes after 14.3 rninutes, the reference item triphenylamine after 3.5 rninutes.
Due to the principle of the HPLC method, reference items will elute the later, the higher the log Pow value is. In conclusion, the test
item exhibits a log Pow value significantly higher than the reference item.
The reference itern triphenylamine is listed in the EU test procedure with the second highest log Pow value (5.7). Furthermore,
the test procedure is only applicable within log Pow values from - 2 to +6.
Thus, based on the prelirninary tests, the following result can be reported:
Log Pow (Sa 190) > 5.7