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EC number: 282-013-3 | CAS number: 84082-68-8 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Myristica fragrans, Myristicaceae.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP study according to NCS protocol.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: NCS protocol
- Deviations:
- no
- Principles of method if other than guideline:
- Visual observation of physical state at different temperatures.
- GLP compliance:
- no
- Type of method:
- other: visual observation
Test material
- Reference substance name:
- Myristica fragrans, ext.
- EC Number:
- 282-013-3
- EC Name:
- Myristica fragrans, ext.
- Cas Number:
- 84082-68-8
- Molecular formula:
- Unspecified (UVCB)
- IUPAC Name:
- Nutmeg Oil (Myristica fragrans, ext.)
- Reference substance name:
- Myristica fragrans, ext.
- IUPAC Name:
- Myristica fragrans, ext.
- Reference substance name:
- 8008-45-5
- IUPAC Name:
- 8008-45-5
- Details on test material:
- - Name of test material (as cited in study report): Nutmeg oil
- Physical state: liquid
Constituent 1
Constituent 2
Constituent 3
Results and discussion
Melting / freezing point
- Key result
- Remarks on result:
- other: Nutmeg oil is a mixture of substances and transition from liquid to solid will not be sharp.
Any other information on results incl. tables
The substance is a clear mobile liquid at 20 degrees Celsius and a clear mobile liquid after 48h at -20 degrees Celsius.
Applicant's summary and conclusion
- Conclusions:
- Nutmeg oil is a clear mobile liquid at 20 degrees Celsius and a clear mobile liquid after 48h at -20 degrees Celsius.
- Executive summary:
Nutmeg oil is a mixture of substances and transition from liquid to solid will not be sharp. The „Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance" from ECHA mentions in chapter R.7.1.2.3, that melting points are not normally carried out for mixtures. Therefore it is recommended in the EFFA/EFEO guideline, the Registration for REACH of Natural Complex Substances used as Fragrance Ingredients" to describe the state of the essential oil after two days at +5°C -if still a liquid the test has to be repeated at -20°C- rather than determining a transition temperature.
The melting point of Nutmeg oil was investigated by visual observation according to the NCS protocol. Nutmeg oil was found to be a clear mobile liquid at 20 degrees Celsius and a clear mobile liquid after 48h at -20 degrees Celsius.
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