Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 278-079-8 | CAS number: 75147-23-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 (48h) of the test item towards Daphnia was 35 mg/L (nominal concentration).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 35 mg/L
Additional information
For this endpoint only one study is available. In this study the acute immobilisation potential of the test item towards Daphnia magna Straus was assessed according to OECD 202.
Over a period of 48 hours 20 test organisms were exposed to a test concentration or a control. The possitive control was potassium dichromate. The nominal tested concentrations were 4.3, 9.4, 20.7, 45.5, 100 mg/L.
The test item was clearly dissolved throughout exposure.The 48 h EC10 and EC50 values with confidence limit (CI) were calculated by probit analysis. The 48 h EC100 value was determined directly from the test results obtained. The quality criteria were fulfilled.
The EC50 (48h) was determined to be 35 mg/L and the EC10 (48h) was 24 mg/L.
The actual test concentrations were not assessed during the OECD 202 study. However, it is clear from the recent OECD 201 (Toxicity to algae) study that the substance is stable. In the latter test the actual concentrations were measured at the beginning and the end of the experiments.
The measured concentrations did not differ more than 20% except for the lowest concentration tested (0.32 mg/L) which is not relevant for the current test. The highest tested dose in both studies was 100 mg/L. This indicates that the substance is stable and even though the concentrations were validated in the OECD 202 study, the results are reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
