Registration Dossier
Registration Dossier
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EC number: 273-521-6 | CAS number: 68988-22-7 A complex residuum from the distillation of products from the manufacture of dimethyl terephthalate by air oxidation and esterification of p-xylene. It consists of polyphenyl polyesters.
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
The submission substance did not show any signs of acute toxicity in respective short-term tests and was not irritating to skin or eyes.
Information from repeated dose toxicity studies is not available, as these studies are not required, based on provisions according to REACH Annex XI, 3.2 (Substance-tailored, exposure-driven testing). Therefore no basis for deriving DNELs for human health effects is available. No DNELs are derived.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
The submission substance did not show any signs of acute toxicity in respsective short-term tests and was not irritating to skin or eyes.
Information from repeated dose toxicity studies is not available, as these studies are not required, based on provisions according to REACH Annex XI, 3.2 (Substance-tailored, exposure-driven testing). Therefore no basis for deriving DNELs for human health effects is available. No DNELs are derived. Furthermore, as this substance is handled under strictly controlled conditions in industrial settings only, no exposure of the general population can occur.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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