Registration Dossier
Registration Dossier
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EC number: 268-500-3 | CAS number: 68109-88-6
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
In accordance with Section 2 of Annex XI of Regulation (EC) No. 1907/2006 (REACH), it is considered justified to omit the studies required under point 9.3.1 of Annex VIII and 9.3.3 of Annex IX, on the basis that testing is not technically possible.
The substance is known to be poorly soluble in water and appropriate organic solvents. Furthermore, the analytical methods for this substance have limited sensitivity and would not produce a meaningful result. This is demonstrated by the difficulties experienced in the study submitted as supporting information for the data requirement 9.2.2.1 Hydrolysis as a function of pH, where attempts to determine the behaviour of the read across substance DOTO (n-dioctyltin oxide) under hydrolysis using electrospray ionisation mass spectrometry (ESI/MS) did not produce any results due to the difficult nature of the substance. Furthermore, calculation of the adsorption coefficient is not appropriate for organotin substances, as there is currently no QSAR or QSPR validated for such an estimation.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
