Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-698-8 | CAS number: 27859-58-1
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 24 November 2015 to 9 September 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- no
- Analytical monitoring:
- no
- Transformation products:
- not measured
- Key result
- Remarks on result:
- not determinable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- No hydrolysable groups were present, in any of the constituents of the test substance, for estimation of a hydrolysis value.
- Executive summary:
The hydrolysis and the Effect of pH of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 111.
Consideration of the chemical structure and physical properties of the test material led to difficulties in determining a reliable half-life for the hydrolysis test. It was not technically feasible to perform the test therefore, it was decided calculate hydrolysis values using the Estimation Program Interface EPI ver. 4.1.
No hydrolysable groups were present, in any of the constituents of the test substance, for estimation of a hydrolysis value.
Reference
There were no hydrolysable groups present in any of the stated constituents of the test substance that could be used to calculate a hydrolysis value.
Description of key information
No hydrolysable groups were present, in any of the constituents of the test substance, for estimation of a hydrolysis value.
Key value for chemical safety assessment
Additional information
The hydrolysis and the Effect of pH of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 111. The study was assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).
Consideration of the chemical structure and physical properties of the test material led to difficulties in determining a reliable half-life for the hydrolysis test. It was not technically feasible to perform the test therefore, it was decided calculate hydrolysis values using the Estimation Program Interface EPI ver. 4.1.
No hydrolysable groups were present, in any of the constituents of the test substance, for estimation of a hydrolysis value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
