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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 Oct 1992 to 06 Jan 1993
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
other: CIPAC method MT 157.3 (water solubility: flask method)
GLP compliance:
yes
Medium:
ethanol
Solubility:
140 g/L
Temp.:
25 °C
Medium:
acetone
Solubility:
300 g/L
Temp.:
25 °C
Medium:
toluene
Solubility:
200 g/L
Temp.:
25 °C
Medium:
n-octanol
Solubility:
110 g/L
Temp.:
25 °C
Medium:
other: n-hexane
Solubility:
6.3 g/L
Temp.:
25 °C
Test substance stable:
yes
Conclusions:
The solubility in five different organic solvents has been determined ranged from 6.3 g/L in hexane to 140 g/L in ethanol.
Executive summary:

The solubility of test substance has been determined in five organic solvents. As there is no general method available for the determination of the solubility in organic solvents, a procedure similar to that described in CIPAC method MT 157.3 (water solubility: flask method) was used in this study. The solubility was found to range 6.3 g/L in hexane to 140 g/L in ethanol.

Description of key information

The test substance can be considered completely miscible in organic solvents, the solubility ranged from 6.3 g/L in hexane to 140 g/L in ethanol, Rodler 1993

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
6.3 g/L

Additional information