Registration Dossier
Registration Dossier
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EC number: 223-798-4 | CAS number: 4078-19-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a static non GLP short-term toxicity to fish test (BASF SE, 10F0680/895245, 1990) according to DIN 38412 – L15 guideline (equivalent to OECD 203), the 96-hour LC50 of the test substance for Leusciscus idus (Golden Orfe) was determined to be nominal in the range of 100 - 215 mg/L.
Key value for chemical safety assessment
Additional information
The acute toxicity of the test substance to fish Leusciscus idus (Golden Orfe) was determined in a study (BASF SE, 10F0680/895245, 1990) according to DIN 38412 – L15 (1982) guideline (equivalent to OECD 203) under non GLP conditions. In this static short-term toxicity to fish test the test substance was tested in the nominal concentrations of 0 (control), 46.4, 100, 215, 464 and 1000 mg/L. No concentrations of the test substance were measured. This study encompassed one treatment group for the dose rates of the test item and one replicate for the control. Each group contained 10 individuals. A positive control with the reference substance chloroacetamide was used. The test fish were observed after 1, 4, 24, 48, 72 and 96 hours test duration for sublethaI effects and mortality. The water quality parameters (pH, temperature and oxygen content) were determined after 1, 24, 48, 42 and 96 hours. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. There were no toxic effects observed in any treatment group during this test. The LC50 of the reference substance was determined to be 34 mg/L after 48 hours. All validity criteria were met. The 96h-LC50 of the test substance was determined to be nominal in the range of 100 – 215 mg/L.
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