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EC number: 207-005-9 | CAS number: 421-50-1
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 September 2016 - 11 January 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP compliant
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23 March 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 24 August 2009
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- August 1996
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- static method
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL:
- At room temperature
OTHER SPECIFICS:
- Purity/composition correction factor: No correction factor required.
- Test item hanling: No specific handling conditions required, but for practical reason the test item could be kept on ice to avoid evaporation of the material before and between performance of physico-chemical tests. - Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 92 000 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 110 000 Pa
- Conclusions:
- The vapour pressure of 1,1,1-trifluoroacetone measured with the static method was 6.9 x 10E2 mm Hg (9.2 x 10E4 Pa) at 20°C and 8.4 x 10E2 mm Hg (1.1 x 10E5 Pa) at 25°C.
- Executive summary:
Measurement of the vapour pressure of 1,1,1 -trifluoroacetone was performed using a static method according to standardised guidelines (OECD TG 104, EU A.4 and OPPTS 830.7950) under GLP conditions.
The vapour pressure of 1,1,1-trifluoroacetone measured with the static method was 6.9 x 10E2 mm Hg (9.2 x 10E4 Pa, i.e. 920 hPa) at 20°C and 8.4 x 10E2 mm Hg (1.1 x 10E5 Pa, i.e. 1100 hPa) at 25°C.
Reference
The plot of the log PT of the test item as function of the reciprocal temperatures is shown in attached document.
The equation of the curve was: log PT,20 = -1441 x 1/T + 9.88 (r = 0.99996, n = 22). The vapour pressure of the test item at 20°C and at 25°C is given in the following Table and was calculated as the mean of the vapour pressures measured at these temperatures.
Vapour pressure of the test item
| Temperature [°C] | log PT | PT [Pa] | PT [mm Hg] |
20 |
4.96 |
9.2 x 104 | 6.9 x 102 |
| 25 | 5.05 | 1.1 x 105 | 8.4 x 102 |
Description of key information
Measurement of the vapour pressure of 1,1,1 -trifluoroacetone was performed using a static method according to standardised guidelines (OECD TG 104, EU A.4 and OPPTS 830.7950) under GLP conditions.
Key value for chemical safety assessment
- Vapour pressure:
- 110 000 Pa
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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