Registration Dossier
Registration Dossier
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EC number: 205-572-7 | CAS number: 142-92-7
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Data are available on the metabolism of acetate esters (including hexyl acetate) and indicate rapid enzymic hydrolysis in vivo
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
- Absorption rate - oral (%):
- 50
- Absorption rate - dermal (%):
- 50
- Absorption rate - inhalation (%):
- 100
Additional information
An IPCS Review indicates that hexyl acetate would be subject to rapid enzymic hydrolysis in vivo. The results of an in vitro study indicate that inhaled acetate esters including hexyl acetate are likely to be extensively hydrolysed by respiratory tract enzymes, resulting in little systemic exposure to the intact ester.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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