Registration Dossier
Registration Dossier
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EC number: 203-909-2 | CAS number: 111-80-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- An optional toxicity control as suggested by OECD 301F was not performed. The validity of the study is not adversely affected.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Methyl non-2-ynoate
- EC Number:
- 203-909-2
- EC Name:
- Methyl non-2-ynoate
- Cas Number:
- 111-80-8
- Molecular formula:
- C10H16O2
- IUPAC Name:
- methyl non-2-ynoate
- Test material form:
- liquid
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Fresh activated sludge from a biological waste water treatement plant treating predominantly domestic sewage (Bois-de-Bay, Satigny, Switzerland) was used.
The sludge is collected in the morning, washed three times in the mineral medium (by centrifuging at 1000g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day. - Duration of test (contact time):
- 48 d
Initial test substance concentration
- Initial conc.:
- 30 mg/L
- Based on:
- test mat.
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 71
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
Methyl Octyne Carbonate undergoes 71% biodegradation after 28 days (74% after 48 days) in the test conditions. The 10 -day window criterion is also fulfilled (29% biodegradation on day 4 and 61% on day 14).
Methyl Octyne Carbonate did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration.
Therefore Methyl Octine Carbonate should be regarded as readily biodegradable.
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