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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

DAB: LD50 (oral) = 749 mg/kw bw
DAB: LD50 (dermal) = 825 mg/kg bw
DAB: LC50 (rat; inhalation) = 1,131 mg/l

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
749 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
1 131 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
825 mg/kg bw

Additional information

All three routes of exposure (oral, dermal and inhalation) lead to classification for acute toxicity.

Justification for classification or non-classification

LD50 (rats, oral) = 740 mg/kg bw; CLP (300 -2000 mg/kg): Acute oral toxicity Category 4; H302 Harmfull if swallowed

LD50(rabbit, dermal) = 825 mg/kg bw; CLP (200 -1000 mg/kg): Acute dermal toxicity Cat. 3; H311 Toxic in contact with skin

LC50(rat, inhalation) = 1.131 mg/l; CLP (0.5 - 2 mg/l, 4h): Acute inhalation toxicity Cat 2; H330 Fatal if inhaled