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EC number: 203-366-1 | CAS number: 106-14-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From Aug. 17, 2010 to Sept. 29, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to standard guidelines in compliance with GLP.
- Justification for data waiving:
- other:
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- capillary method
Test material
- Reference substance name:
- 12-hydroxystearic acid
- EC Number:
- 203-366-1
- EC Name:
- 12-hydroxystearic acid
- Cas Number:
- 106-14-9
- Molecular formula:
- C18H36O3
- IUPAC Name:
- 12-hydroxyoctadecanoic acid
- Details on test material:
- - Name of test material (as cited in study report): 12-hydroxystearic acid
- Physical state: Solid / white to yellowish
- Certificate of analysis date: April 09, 2010
- Expiration date of the lot/batch: 09 April 2011
- Storage condition of test material: In original container, at room temperature (15 - 25°C), in the dark
Constituent 1
Results and discussion
Melting / freezing point
- Melting / freezing pt.:
- 75 - 78 °C
- Atm. press.:
- ca. 1 atm
- Decomposition:
- no
- Remarks on result:
- other: The melting started at 75.2 °C. At 78.0 °C the final stage of melting was reached. No solid particles were left.
Any other information on results incl. tables
Table 1. Results for the determination of the melting range of 12-hydroxystearic acid
Experiment No. | Stage A [°C] | Stage B [°C] | Stage C [°C] | Stage D [°C] | Stage E [°C] |
1 | 75.2 | 75.8 | 76.5 | 77 | 78.1 |
2 | 75.1 | 76 | 76.7 | 77.4 | 77.8 |
3 | 75.4 | 76.2 | 76.8 | 77.2 | 78.1 |
mean value (n=3): | 75.2°C | 76.0°C | 76.7°C | 77.2°C | 78.0°C |
348.4 K | 349.2 K | 349.8 K | 350.4 K | 351.2 K |
Stage A: Beginning of melting / wet point
Stage B: Shrinking point
Stage C: Collapse point
Stage D: Liquefying point
Stage E: Final stage of melting
Applicant's summary and conclusion
- Conclusions:
- The melting point of test substance was found to be in the range of 75 to 78°C.
- Executive summary:
The melting point of 12-hydroxystearic acid was determined by the capillary method using an electronically-controlled heating system according to OECD Guideline 102, EU Method A.1 and EPA OPPTS 830.7200.
In the preliminary test, a sample of the test material in a capillary glass tube was heated from room temperature with a rate of approximately 10ºC/min. to estimate phase transition temperature. For the actual determination of the melting point, the temperature rise was adjusted to a maximum of 1ºC/min. at about 15 ºC before and after the predetermined phase transition temperature.
The melting point of the test substance was found to be in the range of 75 to 78°C.
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