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EC number: 202-358-5 | CAS number: 94-71-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 15 april 2010 to 28 october 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study, OECD 104 compliant
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
- Temp.:
- 20 °C
- Vapour pressure:
- 12.1 Pa
- Remarks on result:
- other: extrapolated value.
- Conclusions:
- The vapour pressure of Guetol extrapolated at 20 °C is 12.1 Pa.
- Executive summary:
The objective of this study is to determine the vapour pressure of GUETOL following the Commission Directive 92/69/EC – Council Regulation (EC) No. 761/2009- EC A4 method (2009) and OECD Guideline No. 104 (2006).
The method used in this study is the Knudsen cell effusion method coupled to a micro-balance.
The quantity of substance leaving a cell per time unit through an aperture of known size is determined under vacuum conditions such that return of substance into the cell is negligible.
The mass of effused vapour is obtained by determining the loss of mass of the Knudsen cell.
As the logarithm of the vapour pressure of a pure substance is a linear function of the inverse of the temperature, the vapour pressure is determined in a limited temperature range.
The vapour pressure of GUETOL extrapolated at 20 °C is P = 12.1 Pa.
Reference
Results
1. Observations
The mass of sample weighed was16.18 mg for the first assay. The sample was placed in a Knudsen effusion cell with an aperture size of A = 178 µm. Then the cell was placed in the apparatus.
The mass of sample weighed was 21.33 mg for the second assay.
The mass of sample weighed was 21.41mg for the third assay.
Temperature steps at 27°C, 29°C and 31°C were made. The loss of mass was very quick.
The whole test item was evaporated after the experimentation.
2. Vapour pressure results
The vapour pressure of the test item was calculated by the “Knudsen software”. The calculation results are summarized in table 1.
Table1: Summary of the calculation of vapour pressure of the test item
Test temperature t(°C) |
Test temperature T (K) |
1/T(K-1) |
Experimental vapour pressure P(Pa) |
Log P (Pa) |
Knudsen effusion cell size(µm) |
27 |
300.15 |
3.332E-03 |
22.38 |
1.350 |
178 |
29 |
302.15 |
3.310E-03 |
26.57 |
1.424 |
|
31 |
304.15 |
3.288E-03 |
31.41 |
1.497 |
The molecular weight of guetol (pure substance) is 138.17 g/mol.
The graph log P = f (1/T) was then plotted to extrapolate the vapour pressure at 20°C
Description of key information
The vapour pressure of GUETOL extrapolated at 20 °C is 12.1 Pa.
Key value for chemical safety assessment
- Vapour pressure:
- 12.1 Pa
- at the temperature of:
- 20 °C
Additional information
Only one study was available (Defitraces, 2010), and was selected as key study. It is of reliability 1 according to Klimisch scale, since conducted according to OECD 104 guideline and GLP.
The vapour pressure of GUETOL extrapolated at 20°C is 12.1 Pa.
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