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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in soil

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Administrative data

Link to relevant study record(s)

Description of key information

Based on QSAR prediction half life period of phthalylsulfathiazole in Soil was estimated to be 99.2 days which exceeds the EPA criteria of 60 days

Also from the other weight of evidnece study it is found that the substance is 50% degradable in 75 days which also exceeds the EPA criteria of 60 days

Based on these half life values it is concluded that phthalylsulfathiazole is not readily biodegradable (persistent) in Soil.

Key value for chemical safety assessment

Half-life in soil:
99.2 d
at the temperature of:
25 °C

Additional information

Based on QSAR prediction half life period of phthalylsulfathiazole in Soil was estimated to be 99.2 days which exceeds the EPA criteria of 60 days

Also from the other weight of evidnece study it is found that the substance is 50% degradable in 75 days which also exceeds the EPA criteria of 60 days. Other supporting studies where reviewed for biodegradation in water endpoints from reliable sources.

The summary of the results are presented below

 

Sr. No

Endpoint name

Value

Units

Half life

1

% degradation 50 % in 99.2 days

 2

 % degradation  50  %   in 75 days

 3

  % degradation 50   %   in 75 days

 

Based on the above information it can be concluded that the substance is not readily biodegaradable and hence persistent in Soil according to CLP regulation.