Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-772-0 | CAS number: 72-17-3
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Dissociating properties:
- no
- Remarks:
- The test item does fully dissociates in water and does not show any measurable titratable acid or base equilibrium. Therefore it can be considered to be neutral in solution. The test item does not have a pKa in the range of 0-14.
- No.:
- #1
- Temp.:
- 20 °C
- Remarks on result:
- other: The test item does not show any measurable titratable acid or base equilibrium and can be considered to be neutral in solution.
- Conclusions:
- Sodium (S)-lactate does not have a pKa in the range of 0-14.
- Executive summary:
The dissociation constant of the test item was determined according to OECD test guideline 112 with the titration method. The test item fully dissociates in water and does not show any measurable titratable acid or base equilibrium. Therefore, it can be considered to be neutral in solution. Sodium (S)-lactate does not have a pKa in the range of 0-14.
This information is used in a read-across approach in the assessment of the target substance. For justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reference
According to the obtained data, presented in the Appendix, the test item does not show any measurable titratable acid or base equilibrium and can be considered to be neutral in solution.
Description of key information
The dissociation constant of the test item was determined according to OECD test guideline 112 with the titration method. The test item fully dissociates in water and does not show any measurable titratable acid or base equilibrium. Therefore it can be considered to be neutral in solution. Sodium (S)-lactate does not have a pKa in the range of 0-14. The result is considered fully valid also for Sodium lactate.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
