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EC number: 200-662-2 | CAS number: 67-64-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Activated sludge of a predominantly domestic sewage: 30 min EC12=1000 mg/L nominal
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
Reliable results were obtained in studies conducted according to guideline and modifications thereof. The results (low toxicity of acetone to microorganisms) are supported by further reliable studies. In a study conducted according to a modification of OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test) suitable for testing of highly volatile substances, activated sludge of a predominantly domestic sewage was exposed to acetone under static conditions in closed system. The 30 min EC12 was determined to be 1000 mg/L nominal based on respiration. In a further study conducted according to ISO 8192 (Test for Inhibition of Oxygen Consumption by Activated Sludge) and equivalent or similar to OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test), activated sludge was exposed to acetone under static conditions. The 30 min EC50 based on respiration inhibition was determined to be 77.4 mL/L (=61.15 g/L nominal). In further experiments with mixed cultures (75 min BIC=35812 mg/L; 24 h LOEC=10000 mg/L), Pseudomonas putida (16 h NOEC=1700 mg/L), Nitrosomonas (24 h IC50=1200 mg/L), and Paramecium caudatum (4 h LC50=5227 mg/L nominal each) the low toxicity of acetone to microorganisms was confirmed. In a static cell multiplication inhibition test with Entosiphon sulcatum, a 72h-NOEC was determined to be 28 mg/L nominal. This value is regarded as outlier.
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