Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Boric acid
  • IUPAC name: boric acid
  • Other names
EC / List no.:
233-139-2
CAS no.:
10043-35-3
Index number:
005-007-00-2
Molecular formula:
BH3O3
SMILES:
OB(O)O
InChI:
InChI=1S/BH3O3/c2-1(3)4/h2-4H
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
20
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01corr) approved by the European Union, this substance may damage fertility and may damage the unborn child.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may damage fertility or the unborn child.

Breakdown of all 1720 C&L notifications submitted to ECHA

Repr. 1B H360FD Harmonised Classification
Repr. 1A H360
STOT SE 1 H370
STOT RE 1 H372
Skin Irrit. 2 H315
Eye Irrit. 2 H319
STOT RE 2 H373
STOT SE 3 H335
STOT SE 3 H336
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • R

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 57 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Substance of very high concern (SVHC) and included in the candidate list for authorisation.
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 81 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: wood preservation.

This substance is used in the following products: washing & cleaning products, anti-freeze products, heat transfer fluids, lubricants and greases, adhesives and sealants, laboratory chemicals, textile treatment products and dyes, water treatment chemicals and fillers, putties, plasters, modelling clay. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance is used in the following activities or processes at workplace: potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), the low energy manipulation of substances bound in materials or articles, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and open transfer and processing with minerals/metals at elevated temperature.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).

This substance is used in the following products: laboratory chemicals, washing & cleaning products, inks and toners, photo-chemicals and fertilisers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: building & construction work, formulation of mixtures and/or re-packaging, agriculture, forestry and fishing, mining, printing and recorded media reproduction and scientific research and development. This substance is used for the manufacture of: chemicals, mineral products (e.g. plasters, cement), machinery and vehicles and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, mixing in open batch processes, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, non-industrial spraying, treatment of articles by dipping and pouring, batch processing in synthesis or formulation with opportunity for exposure and hand mixing with intimate contact only with personal protective equipment available.

Release to the environment of this substance can occur from industrial use: formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: pH regulators and water treatment products, metal working fluids, lubricants and greases and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, mixing in open batch processes, closed processes with no likelihood of exposure and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation in materials and manufacturing of the substance.

This substance is used in the following products: pH regulators and water treatment products, water treatment chemicals and welding & soldering products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging and building & construction work. This substance is used for the manufacture of: chemicals, mineral products (e.g. plasters, cement), machinery and vehicles, fabricated metal products and metals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers, closed processes with no likelihood of exposure and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Release to the environment of this substance can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, manufacturing of the substance, in processing aids at industrial sites and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, closed, continuous processes with occasional controlled exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, formulation of mixtures, in the production of articles and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • Afton Chemical S.P.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
  • Aknel Group a.s., Prumyslova 222 39137 Chotoviny u Tábora Czech Republic
  • Aries S.p.A., Via Egadi, 5 20144 Milano Italy
  • Arysta LifeScience Germany GmbH, Kölnstr. 107 50321 Brühl Germany Germany
  • Borax Europe Limited, 6 St. James's Square SW1Y 4AD London United Kingdom
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited (Beijing Leili Marine Bioindustry Inc.), Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemische Fabrik Budenheim KG, Rheinstrasse 27 55257 Budenheim RLP Germany
  • Chemoform AG, Heinrich-Otto-Str. 28 73240 Wendlingen Germany
  • Chevron Oronite SA - OR - CVX Japan Ltd, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
  • Chevron Oronite SA - OR - CVX Oronite Cy LLC, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
  • Chevron Oronite SA M/I, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
  • CHIMIGIEN S.r.l., Via Levrini 2 25080 Soiano Del Lago (BS) Italy
  • CIBA VISION GmbH (OR CVCA), Industriering 1 63868 Großwallstadt Bavaria Germany
  • CMK, s.r.o., Sandricka 30 96681 Zarnovica Slovakia
  • Cofermin Rohstoffe GmbH & Co. KG, Alfredstrasse 61 45130 Essen Germany
  • CPH Chemicals BV, Amsterdamseweg 204A 1182HL Amstelveen Netherlands
  • Dalmine SpA, Piazza Caduti 6 luglio 1944, n.1 24044 Dalmine BG Italy
  • DEKRA Assurance Services GmbH OR07, Handwerkstr. 15 70565 Stuttgart Germany
  • ETIMINE SA, 204, Zone Industrielle Scheleck 2 L-3225 Bettembourg Luxembourg Luxembourg
  • FARMA-CHEM S.A., Sindos 57022 Thessaloniki Greece
  • FLUIDRA COMMERCIALE ITALIA SPA UNIPERSONALE, Via Aldo Moro, 10 25124 Brescia Italy
  • FUSION AUTOMATION INC, BARROWS ROAD THE PINNACLES CM19 5FD HARLOW ESSEX United Kingdom
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany
  • Industrie Bitossi, via Pietramarina, 53 50053 sovigliana-vinci (FI) Italy
  • Infineum Italia, Strada di Scorrimento 2 17047 Vado Ligure (SV) Italy
  • Infineum Italia, Strada di Scorrimento 2 17047 Vado Ligure (SV) Italy
  • INQUIDE, S.A., Passeig Sanllehy, 25 08213 Polinyà Barcelona Spain
  • INTERTEC srl, Via Nazionale, 3 52011 BIBBIENA (AR) Italy
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Life Technologies Ltd, 3 Fountain Drive Inchinnan Business Park PA4 9RF Paisley Scotland United Kingdom
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Lubrizol Limited 26, The Knowle Nether Lane DE56 4AN Derby United Kingdom
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • Nippon Gohsei (UK) Limited 2, Soarnol House Saltend HU12 8DS Hull East Yorkshire United Kingdom
  • Nippon Gohsei UK Ltd, Soarnol House Saltend HU12 8DS Hull East Yorkshire United Kingdom
  • Norkem Limited, Norkem House Bexton Lane WA16 9FB Knutsford Cheshire United Kingdom
  • NUKEM Isotopes GmbH, Rodenbacher Str. 47 63755 Alzenau Bavaria Germany
  • OR SEARLES VALLEY MINERALS, 164 avenue Joseph Kessel Centre d'affaires Parkile - Bat 2 78960 Voisins Le Bretonneux France
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Reach Only Representative Ltd (naglus), 20 Bostock Hall CW10 9JN Bostock United Kingdom
  • Rio Tinto Iron & Titanium GmbH (5), Mergenthalerallee 77 65760 Eschborn Hesse Germany
  • SCL ITALIA S.P.A., Via Fabio Filzi 25/A 20124 Milan Italy
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Specialty Electronic Materials Belgium, BVBA OR-1, Sneeuwbeslaan 20 / Pb10 B-2610 Wilrijk Belgium
  • Specialty Electronic Materials Netherlands B.V., Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • SQM Europe N.V., Houtdok – Noordkaai 25a 2030 Antwerpen Belgium
  • Steinbach VertriebsgmbH, Aistinger Str. 2 4311 Schwertberg OOE Austria
  • The Acta Group EU BVBA (BE39), Place du Luxembourg 2 1050 Brussels Belgium
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 Muenchen Germany
  • Benoit Roelants du Vivier, Avenue Stuart Merrill, 54 1190 Brussels Belgium
  • Boromine South America s.l., Polígono Industrial Los Cipreses, Nave 37 12006 Castellon de la Plana Castellon Spain
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Central Eastern Europe Operations GmbH, Erdbergstr. 29 1030 Wien Austria
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • Henkel Norden AB, Gustavslundsvägen 151 A P.O Box 15022 167 15 Bromma Sweden
  • Häffner International GmbH, Steinhöft 5-7 Haus am Hafen, III OG 20459 Hamburg Germany

Other names

  • -
  • 005-007-00-2
  • 15674_10043-35-3
  • acide borique
  • Acidium boricum
  • BORIC ACID
  • Boric acid (H3BO3)
  • boric acid. Trihydroxidoboron
  • Boric acidTrihydrooxidoboron
  • boric acidTrihydroxidoboron
  • Borsäure
  • Bórsav
  • Joint submission 10043-35-3
  • not available
  • Ortho-boric Acid
  • Orthoboric Acid
  • Reaction mass of 7446-20-0 and 77892-00-
  • TRHIOSSOBORIC ACID
  • Trihydroxidoboron
  • Boric acid
  • BORIC ACID 99,9%
  • Boric Acid EC
  • Boric Acid EC S
  • Boric Acid EP
  • Boric Acid FG
  • BORIC ACID FINE GRANULAR
  • Boric Acid Flakes
  • BORIC ACID MSR
  • Boric Acid NF
  • Boric Acid NPS Granular
  • Boric Acid NS
  • Boric Acid Paglietta
  • Boric Acid pH Granular
  • BORIC ACID POWDER
  • Boric Acid R Granular
  • Boric Acid SR Granular
  • Boric Acid Tech Grade Granular
  • Boric Acid Tech Grade Powder
  • Boric Acid Technical Grade
  • kyselina boritá
  • Optibor
  • Optibor HG
  • Optibor TG
  • Optibor TP
  • orthoboric acid

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Crystalline (100%) [2]
C Odour
Odourless (100%) [2]
C Substance type
Inorganic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 2 studies processed
R Melting / freezing point
1 000 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
999.85 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 4 studies submitted
  • 2 studies processed
R Density
1.489 g/cm³ @ 23 °C [2]
R Relative density
1.49 @ 23 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
0 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 4 studies submitted
  • 2 studies processed
R Log Pow
-1.09 @ 22 °C and pH 7.5 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
-1.09 @ 22 °C

Water solubility

Study results
  • 6 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
49.2 g/L @ 20 °C and pH 3.7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
49.2 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Non flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 6 studies submitted
  • 2 studies processed
C Dissociating properties
Yes (100%) [2]
R Dissociation constant
8.94 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
pKa at 20 °C
8.94

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 6
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6 4
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 2.9 mg/L (2)
Intermittent releases (freshwater) 13.7 mg/L (2)
Marine water 2.9 mg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (2)
Sediment (freshwater) No exposure of sediment expected (2)
Sediment (marine water) No exposure of sediment expected (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 5.7 mg/kg soil dw (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 28 studies submitted
  • 4 studies processed
P/RResults
LC50 (4 days) 74 - 79.7 mg/L [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other 20 4
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
LC50 for freshwater fish
79.7 mg/L
LC50 for marine water fish
74 mg/L

Long–term toxicity to fish

Study results
  • 32 studies submitted
  • 22 studies processed
P/RResults
NOEC (34 days) 6.4 mg/L [6]
NOEC (32 days) 11.2 - 44.5 mg/L [4]
LOEC (32 days) 23 mg/L [2]
EC10 (34 days) 6.9 - 18 mg/L [4]
LC10 (34 days) 18.3 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 14 8
Other 10
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 68 studies submitted
  • 46 studies processed
P/RResults
LC50 (4 days) 64 - 544 mg/L [30]
LC50 (48 h) 91 - 165 mg/L [16]
NOEC (4 days) 103 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4 42
Other 16 6
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 20 studies processed
P/RResults
NOEC (42 days) 6.6 - 25.9 mg/L [6]
NOEC (28 days) 16.6 - 43.3 mg/L [24]
NOEC (21 days) 6 - 34.2 mg/L [18]
NOEC (14 days) 13.8 - 14.3 mg/L [12]
NOEC (12 days) 33.1 mg/L [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 18 2
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 50 studies submitted
  • 4 studies processed
P/RResults
EC50 (72 h) 40.2 - 66 mg/L [8]
NOEC (72 h) 17.5 - 27.9 mg/L [6]
LOEC (62.4 h) 70.1 mg/L [2]
EC10 (72 h) 24.5 - 50.7 mg/L [8]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other 42 4
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
52.4 mg/L
EC10 or NOEC for freshwater algae
17.5 mg/L

Toxicity to aquatic plants other than algae

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOEC (10 days) 6.5 mg/L [2]
LOEC (10 days) 3.6 - 19.5 mg/L [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to microorganisms

Study results
  • 18 studies submitted
  • 16 studies processed
P/RResults
EC50 (3 h) 175 - 10 000 mg/L [4]
NOEC (72 h) 10 - 20 mg/L [8]
NOEC (7 h) 100 mg/L [2]
NOEC (3 h) 17.5 - 20 mg/L [4]
LOEC (72 h) 20 - 25 mg/L [6]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 12 6
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC10 or NOEC for microorganisms
10 mg/L

Sediment toxicity

Study results
  • 10 studies submitted
  • 10 studies processed
P/RResults
NOEC (28 days) 37.7 - 201.6 mg/kg sediment dw [18]
NOEC (28 days) 20 - 43 mg/L [10]
NOEC (21 days) 80.6 - 284 mg/kg sediment dw [4]
LOEC (28 days) 37.7 mg/kg sediment dw [2]
LOEC (28 days) 40 - 43 mg/L [6]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 10
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 18 studies submitted
  • 18 studies processed
P/RResults
NOEC (63 days) 19.8 - 78.8 mg/kg soil dw [16]
NOEC (56 days) 5.2 - 98 mg/kg soil dw [20]
NOEC (28 days) 174.8 - 315 mg/kg soil dw [8]
NOEC (14 days) 175 mg/kg soil dw [4]
EC10 (56 days) 70.1 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 18
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 10 studies submitted
  • 8 studies processed
P/RResults
NOEC (35 days) 21.9 - 175 mg/kg bw [12]
NOEC (21 days) 174.8 mg/kg soil dw [2]
NOEC (16 days) 98.2 mg/kg soil dw [2]
EC10 (28 days) 13.8 - 68.1 mg/kg bw [8]
EC10 (21 days) 47.5 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 8
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 46 studies submitted
  • 4 studies processed
P/RResults
NOEC (60 days) 5 mg/kg soil dw [2]
NOEC (21 days) 5.25 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 4
Supporting study 38 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 10 studies submitted
  • 6 studies processed
P/RResults
NOEC (28 days) 419.6 mg/kg soil dw [2]
EC10 (3.4 months) 15.4 - 17.2 mg/kg soil dw [4]
EC10 (28 days) 3 - 226 mg/kg soil dw [12]
EC50 (3.4 months) 17.5 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6 4
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.3 mg/m³ developmental toxicity / teratogenicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 392 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.15 mg/m³ developmental toxicity / teratogenicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 196 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 980 µg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 980 µg/kg bw/day developmental toxicity / teratogenicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 32 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 26 2
Weight of evidence
Other 2
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 0.5 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 16 studies submitted
  • 4 studies processed
P/RResults
LD50 2 600 - 4 080 mg/kg bw (rat) [6]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 4
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 6 studies submitted
  • 4 studies processed
P/RResults
LC50 (5 h) 2.03 mg/L air (rat) [2]
LC50 (4 h) 2.12 mg/L air (rat) [2]
M/CInterpretations of results
Other [4]

inhalation
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 12 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
No adverse effect observed LD50 3 765 mg/kg bw
Inhalation route:
No adverse effect observed LC50 2 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 4
Exposure cons.
Other
Study data: eye
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 38 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 17.5 - 100 mg/kg bw/day [4]
LOAEL (rat): 58.5 - 334 mg/kg bw/day [4]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 36
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 100 mg/kg bw/day (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 40 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study 34
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
No adverse effect observed NOAEL 1 150 mg/kg bw/day (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 4
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 26 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 6
Supporting study 20
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant