Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-933-3
CAS no.:
112-07-2
Index number:
Molecular formula:
C8H16O3
SMILES:
CCCCOCCOC(C)=O
InChI:
InChI=1S/C8H16O3/c1-3-4-5-10-6-7-11-8(2)9/h3-7H2,1-2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
10
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is harmful in contact with skin and is harmful if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is harmful if swallowed.

Breakdown of all 2862 C&L notifications submitted to ECHA

Acute Tox. 4 H312 Harmonised Classification
Acute Tox. 4 H332 Harmonised Classification
Acute Tox. 4 H302
Eye Irrit. 2 H319
STOT SE 3 H335
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 22 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 - 100 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: coating products, inks and toners, polymers and washing & cleaning products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance can be found in complex articles, with no release intended: vehicles. This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), wood (e.g. floors, furniture, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

This substance is used in the following products: inks and toners, coating products, leather treatment products, non-metal-surface treatment products, paper chemicals and dyes, polymers and washing & cleaning products.

This substance is used in the following areas: printing and recorded media reproduction and building & construction work. This substance is used for the manufacture of: chemicals, machinery and vehicles, textile, leather or fur and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and hand mixing with intimate contact only with personal protective equipment available.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products, inks and toners and leather treatment products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and manufacturing of the substance.

This substance is used in the following products: inks and toners, coating products, leather treatment products, non-metal-surface treatment products, paper chemicals and dyes, polymers and washing & cleaning products.

This substance is used in the following areas: printing and recorded media reproduction and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals, plastic products and textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and in the production of articles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, laboratory work, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and formulation of mixtures.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: use only outdoors or in a well-ventilated area; do not eat, drink or smoke when using this product; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Call a poison center or doctor/physician if you feel unwell. Take off contaminated clothing and wash it before reuse. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Rinse the mouth. Follow specific treatment (see label). If swallowed: call a poison center or doctor/physician if you feel unwell. If on skin: wash with soap and water.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • Agfa-Gevaert N.V., Septestraat 27 2640 Mortsel Belgium
  • AKZO Nobel Car Refinishes B.V., Rijksstraatweg 31 2170 BA Sassenheim Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • HP Deutschland GmbH, Schickardstrasse 32 71034 Boeblingen Germany
  • HP Europe B.V., Startbaan 16 DE72 2GD Shardlow Derbyshire Netherlands
  • HP Printing and Computing Solutions S.L., calle de José Echegaray 18 28232 Las Rozas de Madrid (Madrid) Spain
  • INEOS Derivatives Lavera SAS (Oxide), Avenue de la bienfaisance BP6 133117 Lavera France
  • INX DIGITAL Czech, A.S., Do Certous 2621/13 - Hall I2 19300 Prague 20 Horni Pocernice Czech Republic
  • LCNBV-OR-CXV, Delftseplein 27E 3013 AA Rotterdam Netherlands
  • Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
  • Monument Chemical, Haven 1972 Ketenislaan 3 9130 Kallo Belgium
  • OXEA Produktion GmbH & Co. KG, Otto-Roelen-Str. 3 46147 Oberhausen NRW Germany
  • POLYNT S.p.A., via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy
  • POLYNT UK Ltd, Station Road ST13 7EF Cheddleton Nr Leek Staffordshire United Kingdom
  • PPG Europe B.V. - OR7, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Toyo ink europe specialty chemicals, Boulevard Dambourney BP 4 76350 Oissel France

Substance names and other identifiers

2-butoxyethyl acetate
EC Inventory, C&L Inventory, REACH pre-registration
butylglycol acetate
C&L Inventory
(2-butoxyetyl)-acetát (sk)
C&L Inventory
2-butoksietil acetat (sl)
C&L Inventory
2-butoksietil-acetat (hr)
C&L Inventory
2-butoksietilacetatas (lt)
C&L Inventory
2-butoksietilacetāts (lv)
C&L Inventory
2-Butoksietyyliasetaatti; butyyliglykoliasetaatti (fi)
C&L Inventory
2-butoksyetylacetat (no)
C&L Inventory
2-butoksüetüülatsetaat (et)
C&L Inventory
2-butossietil acetato (it)
C&L Inventory
2-butoxietil acetat (ro)
C&L Inventory
2-butoxietil-acetát (hu)
C&L Inventory
2-butoxietylacetat (sv)
C&L Inventory
2-butoxy-ethylacetaat (nl)
C&L Inventory
2-Butoxy-ethylacetat (de)
C&L Inventory
2-butoxyethyl-acetát (cs)
C&L Inventory
2-butoxyethylacetat (da)
C&L Inventory
2-бутоксиетил ацетат (bg)
C&L Inventory
acetato de 2-butoxietilo (es)
C&L Inventory
acetato de butilglicol (es)
C&L Inventory
acetato de éter monobutílico de etilenoglicol (pt)
C&L Inventory
acetato di butilglicol (it)
C&L Inventory
acetato di etilenglicolmonobutiletere (it)
C&L Inventory
acétate d'éther monobutylique d'éthylène-glycol (fr)
C&L Inventory
acétate de 2-butoxyéthyle (fr)
C&L Inventory
acétate de butylglycol (fr)
C&L Inventory
butil-glikol-acetat (hr)
C&L Inventory
butilglicol acetat (ro)
C&L Inventory
butilglikol acetat (sl)
C&L Inventory
butilglikol-acetát (hu)
C&L Inventory
butilglikolacetatas (lt)
C&L Inventory
butilglikolacetāts (lv)
C&L Inventory
butylglycolacetaat (nl)
C&L Inventory
butylglycolacetat (da)
C&L Inventory
butylglykol-acetát (sk)
C&L Inventory
butylglykolacetat (no)
C&L Inventory
butylglykolacetát (cs)
C&L Inventory
Butüülglükoolatsetaat (et)
C&L Inventory
ester 2-butoksyetylowy kwasu octowego (pl)
C&L Inventory
octan 2-butoksyetylu (pl)
C&L Inventory
octan butyloglikolu (pl)
C&L Inventory
οξικός 2-βουτοξυ-αιθυλεστέρας (el)
C&L Inventory
οξικός εστέρας της βουτυλογλυκόλης (el)
C&L Inventory
бутилгликол ацетат (bg)
C&L Inventory
Ethanol, 2-butoxy-, 1-acetate
Other
1-ACETOXY-2BUTOXYETHANE
C&L Inventory
2-butoxyehyl acetate
C&L Inventory
2-butoxyethanol acetate
C&L Inventory
2-Butoxyethyl-acetat
C&L Inventory
Butyl Glycol Acetate
Registration dossier
Ethylene glycol butyl ether acetate
Registration dossier
Ethylene Glycol Monobutyl Ether Acetate
C&L Inventory
Ethylene glycol, monobutyl ether acetate
C&L Inventory
Glycol Ether EBA
Registration dossier
N-[[3-[(4-acetamidophenoxy)methyl]-4-methoxyphenyl]methyl]-N-benzyl-2-hydroxybenzamide
C&L Inventory
Butoxyethyl acetate
Registration dossier
Butyl cellosolve acetate
Registration dossier
Butyl CELLOSOLVE™ Acetate
Registration dossier
butyl glycol acetate (BGA)
Registration dossier
Ethanol, 2-butoxy-, acetate (6CI, 7CI, 8CI, 9CI)
Registration dossier
ethylene glycol butyl acetate (EGBA)
Registration dossier
ethylene glycol butyl ether acetate (EGBEA)
Registration dossier
Glycol monobutyl ether acetate
Registration dossier
n-butoxyethyl acetate
Registration dossier
112-07-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
607-038-00-2
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-63.5 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-64.15 °C

Boiling point

Study results
  • 4 studies submitted
  • 1 study processed
R Boiling point
192.3 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
192.15 °C

Density

Study results
  • 5 studies submitted
  • 1 study processed
R Density
0.942 g/cm³ @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
942

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
49.996 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
50 Pa @ 19.85 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
1.51 @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
1.51 @ 20 °C

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
15 g/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
15 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 3 studies submitted
  • 2 studies processed
R Flash point
78 - 84 °C @ 101.3 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
77.85 °C

Auto flammability

Study results
  • 3 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
270 - 280 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
279.85 °C

Flammability

Study results
  • 3 studies submitted
  • 1 study processed
C Interpretation of results
Non flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
1.303 - 3.063 [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
1.81 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 5 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 304 µg/L (1)
Intermittent releases (freshwater) 560 µg/L (1)
Marine water 30.4 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 90 mg/L (1)
Sediment (freshwater) 2.03 mg/kg sediment dw (1)
Sediment (marine water) 203 µg/kg sediment dw (1)
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 415 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 60 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 20 - 40 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
28 mg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 37 mg/L [1]
EC50 (24 h) 145 mg/L [1]
EC0 (48 h) 10 mg/L [1]
EC0 (24 h) 58 mg/L [1]
EC100 (48 h) 320 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
37 mg/L
EC50 / LC50 for marine invertebrates
100 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC10 (7 days) 30.4 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
30 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 520 - 1 570 mg/L [2]
EC0 (72 h) 300 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
1.57 g/L
EC10 or NOEC for freshwater algae
300 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
IC50 (16 h) 2.8 g/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
964 mg/L
EC10 or NOEC for microorganisms
720 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 333 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 169 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 120 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 102 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 72 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.6 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 36 mg/kg bw/day acute toxicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Absorption values
Dermal: 50 %
Inhalation: 65 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 1 study processed
P/RResults
LD50 1 880 mg/kg bw (rat) [1]
LD0 188 - 1 504 mg/kg bw (rat) [2]
M/CInterpretations of results
Harmful [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 6 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 9 studies submitted
  • 2 studies processed
P/RResults
LC0 (4 h) 400 ppm (rat) [1]
M/CInterpretations of results
Not classified [2]

inhalation
Studies with data
Key study 2
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 1 500 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Harmful [1]

dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study 9
Weight of evidence 2
Other 1
Data waiving
no waivers
Study data: eye
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 7 studies submitted
  • 2 studies processed
P/RResults
NOAEC (rat): 31 - 62.5 ppm [2]
NOAEC (mouse): 31 - 62.5 ppm [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEL (rabbit): 150 mg/kg bw/day [1]

Study data: dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant