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REACH

Evaluation

Compliance checks

What are the target endpoints ECHA is screening in the dossiers?

Under ECHA’s Integrated Regulatory Strategy (see Q&A ID 0646), the compliance check of dossiers related to substances manufactured or imported at more than 100 tonnes per year mainly focuses on eight key information requirements (or properties): genotoxicity, repeated dose toxicity, pre-natal developmental toxicity, reproductive toxicity, carcinogenicity, long-term aquatic toxicity, biodegradation and bioaccumulation.

The goal is to focus on the information requirements (or properties)that matter most for human health and the environment, with special emphasis on those which are related to the persistent, bioaccumulative and toxic (PBT) or carcinogenic, mutagenic or toxic to reproduction (CMR) properties of a substance.

More information on the strategy on compliance checks is available at compliance checks page.

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