Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-786-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 May 2010 to 02 July 2010
- Reliability:
- 1 (reliable without restriction)
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Inhibition control in Ready Biodegradability Test
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 28 d
- Key result
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 34.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: >25% biodegradation (actual 78%) after 14 days in toxicity control
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 54.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: >25% biodegradation (actual 78%) observed in toxicity control after 14 days
- Details on results:
- The degradation in the toxicity flask was 78% after 14 days. Therefore, it can be considered that the test item is not toxic towards the inoculum at the test concentration of 54.4 mg/L. The test item in the 301B study was reported to have a purity of 63.84%, which reflects that the commercial Sophorolipids product is an aqueous solution. Correcting for this purity, gives an actual test concentration for the sophorolipid content (active ingredient) of 34.73mg/L. This concentration can be considered as a NOEC for the toxicity to STP microorganisms.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The toxicity of Sophorolipids to microorganisms was assessed in an inhibition control of a standardised ready test performed according to OECD 301B. Sophorolipids did not inhibit the degradation of the positive control, aniline, at a test concentration of 54.4mg/L (test material, 63.84% purity) or 34.73 mg/L (active ingredient, Sophorolipid content). The latter concentration can be considered the NOEC for the toxicity to STP microorganisms.
Reference
Description of key information
In a ready biodegradability screening study (OECD 301B, key study for the biodegradation endpoint in this dossier), Sophorolipids was found to be readily biodegradable and no toxicity was observed in an inhibition control at a test concentration of 54.4 mg/L. The test item in the 301B study was reported to have a purity of 63.84%, which reflects that the commercial Sophorolipids product is an aqueous solution. Correcting for this purity, gives an actual test concentration for the sophorolipid content (active ingredient) of 34.7mg/L. This concentration can be considered as a NOEC for the toxicity to STP microorganisms.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 34.7 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.