Registration Dossier
Registration Dossier
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EC number: 284-325-5 | CAS number: 84852-15-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- acute dermal toxicity can be waived due to corrosive properties of NP. The range finding toxicity data provided by Smyth et al. are without documentation. The Dermal LD50 = 2031 mg/kg in groups of four male New Zealand white rabbits; exposure period was 24 hours
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-finding toxicity data: list VII
- Author:
- Smyth H. F., Carpenter C. P., Weil C. S., Pozzani U., Striegel J. A. and Nycum J. S.
- Year:
- 1 969
- Bibliographic source:
- Am Ind Hyg Assoc J 30, 470-476
Materials and methods
- Test type:
- standard acute method
Test material
- Reference substance name:
- Nonylphenol
- EC Number:
- 246-672-0
- EC Name:
- Nonylphenol
- Cas Number:
- 25154-52-3
- IUPAC Name:
- 2-nonylphenol
Constituent 1
Results and discussion
Applicant's summary and conclusion
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